2739805-64-0
2739805-64-0
Chemical Structure
NT1-O14B
- CAS. Nr.: 2739805-64-0
- Formula:C40H68N2O4S4
- Molecular Weight:769.24
IUPAC Name: bis(2-(decyldisulfanyl)ethyl) 3,3'-((2-(1H-indol-3-yl)ethyl)azanediyl)dipropionate
InChIKey: LBQUNMQRWYTNHB-UHFFFAOYSA-N
SMILES: O=C(CCN(CCC(OCCSSCCCCCCCCCC)=O)CCC1=CNC2=C1C=CC=C2)OCCSSCCCCCCCCCC
Biological Activity: NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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NT1-O14B | 98.43% | NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research. | ||||||||||||||||||||
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References
- [1]. Ma F, et al. Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection. Sci Adv. 2020 Jul 24;6(30):eabb4429. [Content Brief]
- [2]. Jia Y, et al. Nose-to-Brain Delivery of Circular RNA SCMH1-Loaded Lipid Nanoparticles for Ischemic Stroke Therapy. Adv Mater. 2025 Mar 27:e2500598. [Content Brief]
Keywords
