2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (10968):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W015563R
    (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetic acid (Standard)
    (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetic acid (Standard) is the analytical standard of (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetic acid. This product is intended for research and analytical applications. (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetic acid is a Glycine (HY-Y0966) derivative.
    (R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetic acid (Standard)
  • HY-15391R
    Lucitanib (Standard)
    Lucitanib (Standard) is the analytical standard of Lucitanib. This product is intended for research and analytical applications. Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR, potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively.
    Lucitanib (Standard)
  • HY-W003382R
    4-((3-Hydroxypropyl)amino)-3-nitrophenol (Standard)
    4-((3-Hydroxypropyl)amino)-3-nitrophenol (Standard) is the analytical standard of 4-((3-Hydroxypropyl)amino)-3-nitrophenol. This product is intended for research and analytical applications.
    4-((3-Hydroxypropyl)amino)-3-nitrophenol (Standard)
  • HY-14151R
    Prucalopride (Standard)
    Prucalopride (Standard) is the analytical standard of Prucalopride. This product is intended for research and analytical applications. Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pKis of 8.6 and 8.1 for human 5-HT4a/4b receptors, respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer.
    Prucalopride (Standard)
  • HY-102080R
    SAFit2 (Standard)
    SAFit2 (Standard) is the analytical standard of SAFit2 (HY-102080). This product is intended for research and analytical applications. SAFit2, a chemical probe, is a highly potent, highly selective FK506-binding protein 51 (FKBP51) inhibitor with a Ki of 6 nM and also enhances AKT2-AS160 binding.
    SAFit2 (Standard)
  • HY-103254R
    ML221 (Standard)
    ML221 (Standard) is the analytical standard of ML221 (HY-103254). This product is intended for research and analytical applications. ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
    ML221 (Standard)
  • HY-100036R
    MK-4101 (Standard)
    MK-4101 (Standard) is the analytical standard of MK-4101 (HY-100036). This product is intended for research and analytical applications. MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis.
    MK-4101 (Standard)
  • HY-15066R
    CNQX (Standard)
    CNQX (Standard) is the analytical standard of CNQX. This product is intended for research and analytical applications. CNQX (FG9065) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. CNQX is a competitive non-NMDA receptor antagonist. CNQX blocks the expression of fear-potentiated startle in rats.
    CNQX (Standard)
  • HY-50706AR
    Selumetinib sulfate (Standard)
    Selumetinib (sulfate) (Standard) is the analytical standard of Selumetinib (sulfate). This product is intended for research and analytical applications. Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.
    Selumetinib sulfate (Standard)
  • HY-N0360R
    Dihydrotanshinone I (Standard)
    Dihydrotanshinone I (Standard) is the analytical standard of Dihydrotanshinone I. This product is intended for research and analytical applications. Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.
    Dihydrotanshinone I (Standard)
  • HY-100672R
    SR59230A (Standard)
    SR59230A (Standard) is the analytical standard of SR59230A (HY-100672). This product is intended for research and analytical applications. SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively.
    SR59230A (Standard)
  • HY-N0075R
    (Rac)-Byakangelicin (Standard)
    (Rac)-Byakangelicin (Standard) is the analytical standard of (Rac)-Byakangelicin. This product is intended for research and analytical applications. (Rac)-Byakangelicin is a racemate of Byakangelicin mainly isolated from the genus Angelica. Byakangelicin is an aldose-reductase inhibitor with an IC50 value of 6.2 μM.
    (Rac)-Byakangelicin (Standard)
  • HY-W102547R
    3-Chloro-4-morpholino-1,2,5-thiadiazole (Standard)
    3-Chloro-4-morpholino-1,2,5-thiadiazole (Standard) is the analytical standard of 3-Chloro-4-morpholino-1,2,5-thiadiazole. This product is intended for research and analytical applications.
    3-Chloro-4-morpholino-1,2,5-thiadiazole (Standard)
  • HY-107443R
    I-BET762 carboxylic acid (Standard)
    I-BET762 carboxylic acid (Standard) is the analytical standard of I-BET762 carboxylic acid (HY-107443). This product is intended for research and analytical applications. I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1.
    I-BET762 carboxylic acid (Standard)
  • HY-101358R
    8-M-PDOT (Standard)
    8-M-PDOT (Standard) is the analytical standard of 8-M-PDOT (HY-101358). This product is intended for research and analytical applications. 8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity.
    8-M-PDOT (Standard)
  • HY-100067R
    Quetiapine impurity 1 (Standard)
    Quetiapine N-oxide (Standard) is the analytical standard of Quetiapine N-oxide. This product is intended for research and analytical applications.
    Quetiapine impurity 1 (Standard)
  • HY-45298R
    Fluralaner impurity 2 (Standard)
    4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid (Standard) is the analytical standard of 4-(5-(3,5-Dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid. This product is intended for research and analytical applications.
    Fluralaner impurity 2 (Standard)
  • HY-13866R
    Ro 31-8220 mesylate (Standard)
    Ro 31-8220 mesylate (Standard) is the analytical standard of Ro 31-8220 mesylate (HY-13866). This product is intended for research and analytical applications. Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3β (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. Ro 31-8220 mesylate can also inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, and these effects possess pharmacological properties independent of PKC.
    Ro 31-8220 mesylate (Standard)
  • HY-17410R
    Iloperidone (Standard)
    Iloperidone (Standard) is the analytical standard of Iloperidone. This product is intended for research and analytical applications. Iloperidone (HP 873) is a D2/5-HT2 receptor antagonist. Iloperidone is an atypical antipsychotic for the schizophrenia symptoms.
    Iloperidone (Standard)
  • HY-B1241R
    Dihydrostreptomycin sulfate (Standard)
    Dihydrostreptomycin (sulfate) (Standard) is the analytical standard of Dihydrostreptomycin (sulfate) (HY-B1241). This product is intended for research and analytical applications. Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss.
    Dihydrostreptomycin sulfate (Standard)