1. Anti-infection
  2. Bacterial

Tetracycline hydrochloride 

Cat. No.: HY-B0474 Purity: 99.84%
Data Sheet SDS Handling Instructions

Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a wide range of infections.

For research use only. We do not sell to patients.
Tetracycline hydrochloride Chemical Structure

Tetracycline hydrochloride Chemical Structure

CAS No. : 64-75-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $66 In-stock
1 g $60 In-stock
5 g $90 In-stock
10 g   Get quote  
50 g   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Tetracycline hydrochloride is a broad-spectrum antibiotic used to treat a wide range of infections.

In Vitro

Tetracyclines are broad-spectrum agents, exhibiting activity against a wide range of gram-positive and gram-negative bacteria, atypical organisms such as chlamydiae, mycoplasmas, and rickettsiae, and protozoan parasites. Tetracyclines inhibit bacterial protein synthesis by preventing the association of aminoacyl-tRNA with the bacterial ribosome. Tetracyclines traverse the outer membrane of gram-negative enteric bacteria through the OmpF and OmpC porin channels, as positively charged cation (probably magnesium)-tetracycline coordination complexes [1].

In Vivo

The tetracyclines have applications for the treatment of infections in poultry, cattle, sheep, and swine. In some cases, e.g., for therapeutic treatment of large numbers of poultry reared on commercial farms, the antibiotics are added directly to feed or water or can be administered in aerosols. Tetracyclines could be used as growth promotion or growth enhancement. Tetracyclines are used in aquaculture to control infections in salmon, catfish, and lobsters[2].

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.0794 mL 10.3972 mL 20.7943 mL
5 mM 0.4159 mL 2.0794 mL 4.1589 mL
10 mM 0.2079 mL 1.0397 mL 2.0794 mL
References
Molecular Weight

480.9

Formula

C₂₂H₂₅ClN₂O₈

CAS No.

64-75-5

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 10 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

Purity: 99.84%

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Product Name:
Tetracycline hydrochloride
Cat. No.:
HY-B0474
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