1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Tetracycline hydrochloride

Tetracycline hydrochloride 

Cat. No.: HY-B0474 Purity: 98.94%
Handling Instructions

Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

For research use only. We do not sell to patients.

Tetracycline hydrochloride Chemical Structure

Tetracycline hydrochloride Chemical Structure

CAS No. : 64-75-5

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 72 In-stock
Estimated Time of Arrival: December 31
5 g USD 108 In-stock
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Customer Review

Based on 9 publication(s) in Google Scholar

Other Forms of Tetracycline hydrochloride:

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Description

Tetracycline (hydrochloride) is a broad-spectrum antibiotic, exhibiting activity against a wide range of gram-positive and gram-negative bacteria.

In Vitro

Tetracyclines are broad-spectrum agents, exhibiting activity against a wide range of gram-positive and gram-negative bacteria, atypical organisms such as chlamydiae, mycoplasmas, and rickettsiae, and protozoan parasites. Tetracyclines inhibit bacterial protein synthesis by preventing the association of aminoacyl-tRNA with the bacterial ribosome. Tetracyclines traverse the outer membrane of gram-negative enteric bacteria through the OmpF and OmpC porin channels, as positively charged cation (probably magnesium)-tetracycline coordination complexes [1].

In Vivo

The tetracyclines have applications for the treatment of infections in poultry, cattle, sheep, and swine. In some cases, e.g., for therapeutic treatment of large numbers of poultry reared on commercial farms, the antibiotics are added directly to feed or water or can be administered in aerosols. Tetracyclines could be used as growth promotion or growth enhancement. Tetracyclines are used in aquaculture to control infections in salmon, catfish, and lobsters[2].

Clinical Trial
Molecular Weight

480.90

Formula

C₂₂H₂₅ClN₂O₈

CAS No.

64-75-5

SMILES

O[[email protected]@]1(C(C(C(N)=O)=C2O)=O)[[email protected]@]([[email protected]@H]2N(C)C)([H])C[[email protected]@]([[email protected]](O)(C3=CC=C4)C)([H])C(C(C3=C4O)=O)=C1O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (129.96 mM; Need ultrasonic)

H2O : 50 mg/mL (103.97 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0794 mL 10.3972 mL 20.7943 mL
5 mM 0.4159 mL 2.0794 mL 4.1589 mL
10 mM 0.2079 mL 1.0397 mL 2.0794 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.94%

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Keywords:

TetracyclineBacterialAntibioticInhibitorinhibitorinhibit

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Product Name:
Tetracycline hydrochloride
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HY-B0474
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