Copy Link Print Information

Tetracycline hydrochloride

54 Cited Publications
Customer Review

Based on 54 publication(s) in Google Scholar

Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity. Tetracycline hydrochloride exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline hydrochloride can be used for the research of infections.

For research use only. We do not sell to patients.

  • Purity: 98.66%
  • CAS No.: 64-75-5
  • Formula: C22H25ClN2O8
  • Molecular Weight:480.90
  • Storage:

    -20°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • Tetracycline hydrochloride Chemical Structure
    Tetracycline hydrochloride Chemical Structure
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
  • Experimental Validation Results for Tetracycline hydrochloride
CAS No.: 64-75-5
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Tetracycline hydrochloride:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Tetracycline hydrochloride

More
Customer Validation & Images
Flow CytometryBio/Physico-chemical AssayCell Imaging/StainingMicrobiological AssayWB
  • Bio/Physico-chemical Assay
  • Microbiological Assay
  • WB
  • Microbiological Assay
  • Flow Cytometry
  • Microbiological Assay
  • Microbiological Assay
  • Microbiological Assay
  • WB
  • Cell Imaging/Staining
  • WB
  • Microbiological Assay
  • Flow Cytometry

All Antibiotic Isoforms

More
Keywords
100 mg

Get Quote In-stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Tetracycline hydrochloride Chemical Structure
    Tetracycline hydrochloride Chemical Structure
    1/16
  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: iScience. 2025 Nov 17;28(12):114102. [Abstract]

    Customer Validation
     We performed dual RNA-seq on phorbol 12-myristate 13-acetate (PMA)-differentiated THP-1 macrophages sub-populations infected with double-fluorescent-engineered H37Ra in vitro. This strain constitutively expressed Emerald (green) and expressed TagRFP (red) only upon Tetracycline hydrochloride induction, enabling discrimination of bacterial viability by fluorescence-activated cell sorting (FACS).

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: AMB Express. 2024 Dec 24;14(1):141. [Abstract]

    Customer Validation
     Combinational antimicrobial effects between PVB and conventional antibiotics against MRSA ATCC 43,300. TET, Tetracycline. DOX, Doxycycline. E, Erythromycin. AZI, Azithromycin. P, Penicillin. CAZ, Ceftazidime. AMP, Ampicillin. CEZ, Cefazolin. CEF, Cefotaxime. OXA, Oxacillin. CRO, Ceftriaxone. AMK, Amikacin. GEN, Gentamycin, KANA, Kanamycin. TOB, Tobramycin. SPC, Spectinomycin.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: J Extracell Vesicles. 2024 Jul;13(7):e12468. [Abstract]

    Customer Validation
     The protein levels of HEXB in HBV replication cell model. Left, Tetracycline was added to inhibit HBV replication in HepAD38 cells. Right, HepG2.2.15 was treated with NAC (1 mM, 12 h) to abolish ROS produced by HBV replication.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: Microorganisms. 2024 Mar 13;12(3):575. [Abstract]

    Customer Validation
     Percentages of E. coli strains showing antimicrobial resistance to different antimicrobial agents. AMP, Ampicillin; CAZ, Ceftazidime; IPM, Imipenem; MRP, Meropenem; GEN, Gentamicin; OFX, Ofloxacin; SXT, Trimethoprim–sulfamethoxazole; TET, Tetracycline; TGC, Tigecycline; CL, Colistin; FFC, Florfenicol.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: J Clin Invest. 2023 Apr 17;133(8):e159941. [Abstract]

    Customer Validation
     THP-1–derived macrophages were infected for 72 hours with Mtb strain H37Ra carrying a dual-color reporter that comprises a constitutively green (Emerald) and a Tetracycline-inducible red (TagRFP) fluorescent protein. Tetracycline (500 ng/mL) was added 24 hours before analysis of the live or dead status of the H37Ra strain in macrophages by flow cytometry.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: EBioMedicine. 2022 Apr;78:103943. [Abstract]

    Customer Validation
     Microdilution checkerboard analysis showed that plumbagin restored the susceptibility of tet(X4)-carrying E. coli J53p47EC and K. pneumoniae K12016p47EC to Tetracycline, in comparison to the tet(X4)-negative strains E. coli J53 and K. pneumoniae K12016.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: EBioMedicine. 2022 Apr;78:103943. [Abstract]

    Customer Validation
     Time-killing assays of resistant E. coli DH5α+pAM401-tet(X4) by a combination of Tetracycline (8 μg/mL, 0-24 h) and Plumbagin.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: EBioMedicine. 2022 Apr;78:103943. [Abstract]

    Customer Validation
     Synergistic mechanisms of plumbagin in combination with tetracycline. An accelerated TCA cycle was observed after the treatment with the combination of Plumbagin and Tetracycline (16 and 32 μg/mL).

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Res. 2020 Dec;30(12):1063-1077. [Abstract]

    Customer Validation
     Immunoblotting analysis of MLKL-Flag, tBid-Flag, and Cleaved Caspase-3 expression in cell death-inducible C2C12 cell lines with or without tetracycline treatment. C2C12-Mlkl-TetON cells were treated with 1 μg/mL Tetracycline hydrochloride for 12 h to induce necroptosis, and C2C12-tBid-TetON cells were treated with 1 μg/mL Tetracycline hydrochloride for 6 h to induce apoptosis.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Res. 2020 Dec;30(12):1063-1077. [Abstract]

    Customer Validation
     Representative phase-contrast images of MuSCs cultured in different fractions of NCM after purification. The complete NCM was used as the positive control (NCM input); C2C12-Mlkl-TetON medium without Tetracycline hydrochloride treatment was used as the negative control (Tet-control). Cells were cultured for 48 h. Scale bars, 100 μm.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: Cell Res. 2020 Dec;30(12):1063-1077. [Abstract]

    Customer Validation
     Immunoblotting analysis of the expression and extracellular release of TNC upon necroptosis induction at different time points as indicated. C2C12-Mlkl-TetON cells were treated with 1 μg/mL Tetracycline hydrochloride for 12 h to induce necroptosis. Both the whole cell lysates and NCM were harvested and then subjected to immunoblotting analysis using antibodies as indicated.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2020 Jul 21;7(17):2001374. [Abstract]

    Customer Validation
     The pEt_20 polymer mitigates resistance to Azithromycin, Gentamicin, Imipenem, and Tetracycline, and reduces their minimum inhibitory concentration (MIC) to sensitive levels or even lower.

  • 1/16

    Tetracycline hydrochloride purchased from MedChemExpress. Usage Cited in: MBio. 2019 Aug 27;10(4). pii: e01949-19. [Abstract]

    Customer Validation
     CD157 deficiency impairs macrophage bactericidal capacity. Peritoneal macrophages from WT mice and Cd157 KO mice treated with sCD157 (+sCD157) (5 μg/ml) or not treated with sCD157 were infected with strain H37Ra harboring a dual-color reporter that comprises a constitutively green (Emerald) and a Tetracycline hydrochloride-inducible red (TagRFP) fluorescent protein for 3 days. Tetracycline hydrochloride (500 ng/ml) was added 24 h before flow cytometry. Macrophages were then harvested and fixed with 4% PFA, and the percentage of cells with live M. tuberculosis (MTB) (red) were determined by FACS.

  • Tetracycline hydrochloride