Sabizabulin hydrochloride (Synonyms: VERU-111 hydrochloride; ABI-231 hydrochloride)

Cat. No.: HY-120599A: Ficha de datos Instrucciones de manejo
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Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC₅₀ of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects.

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Sabizabulin hydrochloride Estructura química

No. CAS : 2635953-17-0

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Other In-stock Forms of Sabizabulin hydrochloride:

Sabizabulin

Other Forms of Sabizabulin hydrochloride:

Sabizabulin In-stock

4 Publications Citing Use of MCE Sabizabulin hydrochloride

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Descripciòn	Sabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC₅₀ of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects^[1].
Peso molecular	413.85
Fòrmula	C₂₁H₂₀ClN₃O₄
No. CAS	2635953-17-0
SMILES	O=C(C1=CN=C(C2=CNC3=C2C=CC=C3)N1)C4=CC(OC)=C(C(OC)=C4)OC.Cl
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (269 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1 H-Indol-3-yl)-1 H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin [Content Brief]

Sabizabulin hydrochloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sabizabulin2635953-17-0VERU-111ABI-231VERU111VERU 111ABI231ABI 231Microtubule/TubulinHPVEndogenous MetaboliteApoptosisHuman papillomavirusInhibitorinhibitorinhibit

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Sabizabulin hydrochloride (Synonyms: VERU-111 hydrochloride; ABI-231 hydrochloride)

Other Forms of Sabizabulin hydrochloride:

Sabizabulin hydrochloride Related Antibodies

4 Publications Citing Use of MCE Sabizabulin hydrochloride

Recomendaciones destacadas

•Related Small Molecules:

•Related Proteins:

Ver todos los productos específicos de isoformas Endogenous Metabolite:

Actividad biológica

Pureza y Documentación

Referencias

Revisión del cliente

Sabizabulin hydrochloride Related Classifications

Calculadora de molaridad

Calculadora de dilución