2. Anticorps inhibiteurs
  3. In Vivo Antibodies
  4. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) 

Cat. No.: HY-P990120 Pureté: 99%
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Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) is an anti-rat Kappa Immunoglobulin Light Chain IgG2a monoclonal antibody. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance B cell depletion. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance T cell exhaustion after the injection of CD4 mAb (HY-P990792) and CD8 mAb (HY-P99129). Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can be used for research on immunology.

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Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) Chemical Structure

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Description

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) is an anti-rat Kappa Immunoglobulin Light Chain IgG2a monoclonal antibody. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance B cell depletion. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance T cell exhaustion after the injection of CD4 mAb (HY-P990792) and CD8 mAb (HY-P99129). Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can be used for research on immunology[1][2].

Isotype

Mouse IgG2a kappa
Recommend Isotype Controls
Species Reactivity

Rat
In Vivo

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) (150 μg/mouse, i.p., single dose, 48 h after injection of CD19/CD22/B220 mAb) can enhance B cell depletion in Col7a1-tetO-H2B-mCherry mice[1].
Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) (100 or 200μg, i.p., single dose, 1 h after injection of CD4/CD8 mAb) enhances the depletion of CD4+ or CD8+ T cells after injection of CD4/CD8 mAb in female DBA/1 mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Col7a1-tetO-H2B-mCherry mice[1]
Dosage: 150 μg/mouse
Administration: Intraperitoneal injection (i.p.), single dose, 48 h after injection of CD19/CD22/B220 mAb
Result: Significantly reduced the number of B cells.
Animal Model: Female DBA/1 mice (8-12 weeks)[2]
Dosage: 100 or 200 μg
Administration: Intraperitoneal injection (i.p.), single dose, 1 h after injection of CD4/CD8 mAb
Result: Significantly exhausted CD4+ or CD8+ T cells, reducing the proportion to below 5 %.
Application

in vivo B cell depletion in combination with anti-CD19 (clone 1D3) and anti-CD22 (clone Cy34.1)
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Masse moléculaire

150 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)]
Formulation

Please refer to the lot-specific COA for specific buffer information.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)OthersKappa Immunoglobulin Light ChainB cellT cellInhibitorinhibitorinhibit

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Nom du produit:
Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)
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HY-P990120
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