CXCL11 Antibody (YA1769)

Cat. No.: HY-P82024: Ficha de datos COA
SDS
User Guide for Antibodies
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Technical Support

CXCL11 Antibody (YA1769) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL11.

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Tamaño	Stock	Cantidad
Muestra gratis	Apply now
10 μL	En stock	Estimated Time of Arrival: December 31
50 μL	En stock	Estimated Time of Arrival: December 31
100 μL	En stock	Estimated Time of Arrival: December 31
250 μL	Obtener un presupuesto

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CXCL11 Antibody (YA1769) Recomendaciones destacadas:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Descripciòn

Descripciòn

CXCL11 Antibody (YA1769) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL11.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Peso molecular

Predicted band size: 10 kDa;

Observed band size: 15 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O14625

Gene ID

6373 [NCBI]

Immunogen

A synthesized peptide derived from human CXCL11 aa20-65/94.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Pureza	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from THP-1(lane 2(20ug) and THP-1(lane 3(40ug) using CXCL11 Antibody (HY-P82024) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

Function：Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses

Subcellular Localization：Secreted

Expression：
Tissue_specificity:High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders

Induction:By IFNG/IFN-gamma and IFNB1/IFN-beta. Induction by IFNG/IFN-gamma is enhanced by TNF in monocytes, dermal fibroblasts and endothelial cells, and by IL1/interleukin-1 in astrocytes

Subunit：Interacts with TNFAIP6 (via Link domain)

RRID

AB_3104145

Database

Entrez Gene: 6373 Human

SwissProt: O14625 Human

OMIM: 604852 Human

Research Field

Immunology

Synonyms

betaR; CXC11; CXCL11; H174; I TAC; IP9; ITAC; SCYB11; SCYB9B

Documentación

Select Batch:

Ficha de datos (234 KB) SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

CXCL11 Antibody (YA1769) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CXCL11 Antibody (YA1769)

CXCL11 Antibody (YA1769) Recomendaciones destacadas:

Product Detail

Verification Image

Background

Descripciòn

CXCL11 Antibody (YA1769) Related Classifications

Productos vistos recientemente:

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