1. Neuronal Signaling Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. Bedinvetmab

Bedinvetmab  (Synonyms: ZTS-00508841)

製品番号: HY-P99297 純度: 99.80%
COA Technical Support

Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs.

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CAS 番号 : 2171034-69-6

容量 価格(税別) 在庫状況 数量
>無料サンプル (100 μg)   今すぐ申し込む  
1 mg $300 在庫あり
5 mg $780 在庫あり
10 mg $1250 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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製品説明

Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs[1][2].

Isotype

IgG2-lambda

Species Reactivity

Canlupfam

IC50 & Target

Canlupfam NGF

体内実験

Bedinvetmab (0.5-1 mg/kg; s.c. for 28 d) alleviates the pain associated with canine osteoarthritis[1].
Bedinvetmab (1 mg/kg; s.c. monthly; 3× and 10× dose multiples) is well tolerated in normal laboratory Beagle dogs for 6 months and with 2 weeks' concurrent NSAID administration[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

145.34 kDa

CAS 番号
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bedinvetmab]

輸送条件

Shipping with dry ice.

保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG2-lambda
純度とドキュメンテーション
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Bedinvetmab
製品番号:
HY-P99297
数量:
MCE 日本正規代理店: