2171034-69-6
2171034-69-6
Chemical Structure
Bedinvetmab
Synonym(s): ZTS-00508841
- CAS No.: 2171034-69-6
- Formula:N/A
- Molecular Weight:(145.34 kDa)
IUPAC Name: (4-bromo-3-fluorophenethoxy)(tert-butyl)dimethylsilane
SMILES: [Bedinvetmab]
Biological Activity: Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs[1][2].
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Bedinvetmab | 99.80% | Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs. | ||||||||||||||||||||
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References
- [1]. Corral MJ, et, al. A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab, a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis. Vet Anaesth Analg. 2021 Nov;48(6):943-955. [Content Brief]
- [2]. Krautmann M, et, al. Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs. Vet J. 2021 Oct;276:105733. [Content Brief]
