2. Neuronal Signaling Protein Tyrosine Kinase/RTK
  3. Trk Receptor
  4. Bedinvetmab

Bedinvetmab  (Synonyms: ZTS-00508841)

Cat. No.: HY-P99297 Purity: 99.80%
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Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs.

For research use only. We do not sell to patients.

Bedinvetmab Chemical Structure

Bedinvetmab Chemical Structure

CAS No. : 2171034-69-6

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Based on 1 publication(s) in Google Scholar

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Description

Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs[1][2].

In Vivo

Bedinvetmab (0.5-1 mg/kg; s.c. for 28 d) alleviates the pain associated with canine osteoarthritis[1].
Bedinvetmab (1 mg/kg; s.c. monthly; 3× and 10× dose multiples) is well tolerated in normal laboratory Beagle dogs for 6 months and with 2 weeks' concurrent NSAID administration[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Bedinvetmab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.80%

COA (231 KB)

Handling Instructions (2659 KB)
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Bedinvetmab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bedinvetmab2171034-69-6ZTS-00508841ZTS00508841ZTS 00508841Trk ReceptorTropomyosin related kinase receptorcaninemAbNGFtrkAp75NTRosteoarthritispaindogInhibitorinhibitorinhibit

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