2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Autophagy
  3. RAR/RXR Autophagy
  4. Bexarotene-d4

Bexarotene-d4  (Synonyms: LGD1069 d4)

製品番号: HY-14171S 純度: 98.51%
COA 取扱説明書 Technical Support

Bexarotene-d4 is a deuterium labeled Bexarotene (LGD1069). Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.

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Bexarotene-d<sub>4</sub>

Bexarotene-d4 構造式

CAS 番号 : 2182068-00-2

容量 価格（税別） 在庫状況 数量
1 mg $250 在庫あり
5 mg $880 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
10 mg $1540 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Other Forms of Bexarotene-d4:

Bexarotene-d4 関連抗体

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RAR/RXR アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
RXRα RXRβ RXRγ

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製品説明

Bexarotene-d4 is a deuterium labeled Bexarotene (LGD1069). Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma[1][2][3][4][5].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

分子量

352.50

分子式

C24H24D4O2
CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

CC1(C2=C(C(C)(CC1)C)C=C(C(C(C3=C([2H])C([2H])=C(C([2H])=C3[2H])C(O)=O)=C)=C2)C)C
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMF : ≥ 20 mg/mL (56.74 mM)

DMSO : ≥ 10 mg/mL (28.37 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : ≥ 0.5 mg/mL (1.42 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8369 mL 14.1844 mL 28.3688 mL
5 mM 0.5674 mL 2.8369 mL 5.6738 mL
10 mM 0.2837 mL 1.4184 mL 2.8369 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO / DMF 1 mM 2.8369 mL 14.1844 mL 28.3688 mL 70.9220 mL
DMSO / DMF 5 mM 0.5674 mL 2.8369 mL 5.6738 mL 14.1844 mL
10 mM 0.2837 mL 1.4184 mL 2.8369 mL 7.0922 mL
15 mM 0.1891 mL 0.9456 mL 1.8913 mL 4.7281 mL
20 mM 0.1418 mL 0.7092 mL 1.4184 mL 3.5461 mL
25 mM 0.1135 mL 0.5674 mL 1.1348 mL 2.8369 mL
DMF 30 mM 0.0946 mL 0.4728 mL 0.9456 mL 2.3641 mL
40 mM 0.0709 mL 0.3546 mL 0.7092 mL 1.7730 mL
50 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.4184 mL
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Bexarotene-d4 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bexarotene-d42182068-00-2LGD1069 d4RAR/RXRAutophagyRetinoic acid receptorsRetinoid X receptorsT-celllymphomabreastcancerCTCLInhibitorinhibitorinhibit

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製品名:
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製品番号:
HY-14171S
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