1. Metabolic Enzyme/Protease
    Autophagy
  2. RAR/RXR
    Autophagy
  3. Bexarotene

Bexarotene (Synonyms: LGD1069)

Cat. No.: HY-14171 Purity: 99.81%
Handling Instructions

Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.

For research use only. We do not sell to patients.

Bexarotene Chemical Structure

Bexarotene Chemical Structure

CAS No. : 153559-49-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
50 mg USD 72 In-stock
Estimated Time of Arrival: December 31
100 mg USD 108 In-stock
Estimated Time of Arrival: December 31
500 mg USD 348 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Top Publications Citing Use of Products

    Bexarotene purchased from MCE. Usage Cited in: Cell Physiol Biochem. 2016;40(5):1239-1251.

    Arithmetic means±SEM (n=14) of erythrocyte annexin-V-binding following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) bexarotene (0.2-0.6 µg/mL). For comparison, the effect of the solvent DMSO is shown (grey bar).

    Bexarotene purchased from MCE. Usage Cited in: Neurobiol Dis. 2018 Sep;117:114-124.

    Bexarotene increases neuronal maintenance and inhibits cell apoptosis after controlled cortical impact (CCI). Representative Western blotting images of cleaved caspase-3, Bax and Bcl-2 in ipsilateral brain on the 14th day after CCI.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.

    Clinical Trial
    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 60 mg/mL (172.18 mM; Need ultrasonic)

    H2O : < 0.1 mg/mL (insoluble)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.8696 mL 14.3480 mL 28.6961 mL
    5 mM 0.5739 mL 2.8696 mL 5.7392 mL
    10 mM 0.2870 mL 1.4348 mL 2.8696 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.08 mg/mL (5.97 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References
    Molecular Weight

    348.48

    Formula

    C₂₄H₂₈O₂

    CAS No.

    153559-49-0

    SMILES

    CC1(C2=C(C(C)(CC1)C)C=C(C(C(C3=CC=C(C=C3)C(O)=O)=C)=C2)C)C

    Shipping

    Room temperature in continental US; may vary elsewhere

    Purity: 99.81%

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    The molarity calculator equation

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Product Name:
    Bexarotene
    Cat. No.:
    HY-14171
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    Bexarotene

    Cat. No.: HY-14171