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Bexarotene-¹³C₄

(Synonyms: LGD1069-¹³C₄)

Bexarotene-¹³C₄ (LGD1069-¹³C₄) is the ¹³C-labeled Bexarotene (HY-14171). Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC₅₀s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC₅₀ >10000 nM). Bexarotene can be used for the research of cutaneous T-cell lymphoma.

For research use only. We do not sell to patients.

CAS No.: 1185030-01-6
Formula: C₂₀¹³C₄H₂₈O₂
Molecular Weight:352.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (245 KB)

Bexarotene-¹³C₄ Chemical Structure

CAS No.: 1185030-01-6

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Biological Activity

Description

Bexarotene-¹³C₄ (LGD1069-¹³C₄) is the ¹³C-labeled Bexarotene (HY-14171). Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC₅₀s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC₅₀ >10000 nM)^[1]^[2]^[3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.

All RAR/RXR Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1185030-01-6
Unlabeled Cas 153559-49-0
Molecular Weight 352.45
Formula C₂₀¹³C₄H₂₈O₂
SMILES

C=C(C1=CC2=C(C([13CH3])(CCC2([13CH3])[13CH3])[13CH3])C=C1C)C3=CC=C(C=C3)C(O)=O
Synonyms

LGD1069-¹³C₄
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.