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Cat. No.: HY-W777169

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Bexarotene-¹³C₄

Name: Bexarotene-13C4
Brand: MedChemExpress
SKU: HY-W777169
Price: 501.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: LGD1069-¹³C₄)

Bexarotene-¹³C₄ (LGD1069-¹³C₄) is the ¹³C-labeled Bexarotene (HY-14171). Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC₅₀s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC₅₀ >10000 nM). Bexarotene can be used for the research of cutaneous T-cell lymphoma.

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CAS No.: 1185030-01-6
Formule: C₂₀¹³C₄H₂₈O₂
Masse moléculaire:352.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (245 KB)

Bexarotene-¹³C₄ Chemical Structure

CAS No.: 1185030-01-6

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Activité biologique
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- In Vitro
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Chemical Information
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Activité biologique

Description

Bexarotene-¹³C₄ (LGD1069-¹³C₄) is the ¹³C-labeled Bexarotene (HY-14171). Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC₅₀s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC₅₀ >10000 nM)^[1]^[2]^[3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.

Voir tous les produits spécifiques à Isoform RAR/RXR :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1185030-01-6
Unlabeled CAS 153559-49-0
Masse moléculaire 352.45
Formule C₂₀¹³C₄H₂₈O₂
SMILES

C=C(C1=CC2=C(C([13CH3])(CCC2([13CH3])[13CH3])[13CH3])C=C1C)C3=CC=C(C=C3)C(O)=O
Synonyms

LGD1069-¹³C₄
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.