2. Cell Cycle/DNA Damage Anti-infection
  3. DNA/RNA Synthesis Bacterial
  4. Citrocin

Citrocin is a potent bacterial RNA polymerase (RNAP) inhibitor. Citrocin shows significant inhibitory activity against Escherichia coli RNAP with an MIC range of 16-125 μM. Citrocin specifically binds to and inhibits RNA polymerase to block bacterial transcription and enters cells mainly through inner membrane protein SbmA. Citrocin is promising for research of Gram-negative bacterial infections, such as enterohemorrhagic E. coli.

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Custom Peptide Synthesis

Citrocin

Citrocin 화학구조

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Citrocin Related Antibodies

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제품 설명

Citrocin is a potent bacterial RNA polymerase (RNAP) inhibitor. Citrocin shows significant inhibitory activity against Escherichia coli RNAP with an MIC range of 16-125 μM. Citrocin specifically binds to and inhibits RNA polymerase to block bacterial transcription and enters cells mainly through inner membrane protein SbmA. Citrocin is promising for research of Gram-negative bacterial infections, such as enterohemorrhagic E. coli[1].

IC50 & Target

RNA Polymerase

 

분자량

1881.14

화학식

C88H133N23O23
Sequence

cyclo{Gly-Gly-Val-Gly-Lys-Ile-Ile-Glu}-Tyr-Phe-Ile-Gly-Gly-Gly-Val-Gly-Arg-Tyr-Gly
Sequence Shortening

cyclo{GGVGKIIE}YFIGGGVGRYG
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Citrocin Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CitrocinDNA/RNA SynthesisBacterialRNAPSbmAGram-negative bacterial infectionsInhibitorinhibitorinhibit

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상품명:
Citrocin
Cat. No.:
HY-P10980
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