2. Membrane Transporter/Ion Channel Neuronal Signaling Immunology/Inflammation
  3. nAChR Interleukin Related
  4. Cynandione A

Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression.

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Cynandione A

Cynandione A 構造式

CAS 番号 : 168706-29-4

容量 価格（税別） 在庫状況 数量
1 mg $192 在庫あり
5 mg $480 お問い合わせ
10 mg $835 お問い合わせ
25 mg $1555 お問い合わせ
50 mg   お問い合わせ  
100 mg   お問い合わせ  

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Cynandione A 関連抗体

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

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製品説明

Cynandione A is an acetophenone that can be isolated from Cynanchum Wilfordii Radix. Cynandione A protects hepatocytes and cortical neurons from toxicity and improves neurological deficits in a rat model of cerebral ischemia. On the other hand, cynandione A has significant anti-inflammatory effects and inhibits inflammation by activating macrophage α7 nAChR and IL-10 expression[1].

分子量

302.28

分子式

C16H14O6
CAS 番号
Appearance

Solid

Color

White to light yellow

SMILES

CC(C1=C(O)C(C2=C(O)C=CC(O)=C2C(C)=O)=C(O)C=C1)=O
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 40 mg/mL (132.33 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3082 mL 16.5410 mL 33.0819 mL
5 mM 0.6616 mL 3.3082 mL 6.6164 mL
10 mM 0.3308 mL 1.6541 mL 3.3082 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

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体積 （開始）

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濃度 （終了）

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体積 （終了）

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3082 mL 16.5410 mL 33.0819 mL 82.7048 mL
5 mM 0.6616 mL 3.3082 mL 6.6164 mL 16.5410 mL
10 mM 0.3308 mL 1.6541 mL 3.3082 mL 8.2705 mL
15 mM 0.2205 mL 1.1027 mL 2.2055 mL 5.5137 mL
20 mM 0.1654 mL 0.8270 mL 1.6541 mL 4.1352 mL
25 mM 0.1323 mL 0.6616 mL 1.3233 mL 3.3082 mL
30 mM 0.1103 mL 0.5514 mL 1.1027 mL 2.7568 mL
40 mM 0.0827 mL 0.4135 mL 0.8270 mL 2.0676 mL
50 mM 0.0662 mL 0.3308 mL 0.6616 mL 1.6541 mL
60 mM 0.0551 mL 0.2757 mL 0.5514 mL 1.3784 mL
80 mM 0.0414 mL 0.2068 mL 0.4135 mL 1.0338 mL
100 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8270 mL
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Cynandione A Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cynandione A168706-29-4nAChRInterleukin RelatedNicotinic acetylcholine receptorsILHepatocytescortical neuronsnerve damageanti-inflammatorycerebral ischemia in ratsInhibitorinhibitorinhibit

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製品名:
Cynandione A
製品番号:
HY-N8249
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