2. Anti-infection
  3. HIV
  4. Decanoyl-RVKR-CMK

Decanoyl-RVKR-CMK  (Synonyms: DecRVKRcmk)

製品番号: HY-107760 純度: 99.64%
COA 取扱説明書 Technical Support

Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication.

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Decanoyl-RVKR-CMK

Decanoyl-RVKR-CMK 構造式

CAS 番号 : 150113-99-8

容量 価格（税別） 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 1065 在庫あり
Solution
10 mM * 1 mL in DMSO USD 1065 在庫あり
Solid
1 mg $260 在庫あり
5 mg $650 在庫あり
10 mg $1050 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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Based on 1 publication(s) in Google Scholar

Other Forms of Decanoyl-RVKR-CMK:

Decanoyl-RVKR-CMK 関連抗体

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HIV アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示
HIV HIV-1 HIV-2

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製品説明

Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits over-expressed gp160 processing and HIV-1 replication[1].

Cellular Effect
Cell Line Type Value Description References
Vero IC50
11.5 μM
Compound: Dec-RVKR-CMK
Inhibition of furin in African green monkey Vero cells assessed as protection against Stx-induced toxicity incubated for 4 hrs prior to Stx challenge measured after 24 hrs by LDH assay
Inhibition of furin in African green monkey Vero cells assessed as protection against Stx-induced toxicity incubated for 4 hrs prior to Stx challenge measured after 24 hrs by LDH assay
[PMID: 24359257]
体外実験

Decanoyl-RVKR-CMK (DecRVKRcmk) inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell[1].
Decanoyl-RVKR-CMK (DecRVKRcmk) blocks regulated secretion of VGF[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Decanoyl-RVKR-CMK 関連抗体

Cell Viability Assay[1]

Cell Line: HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL.
Concentration: 35 and 70 µΜ.
Incubation Time: 7 days.
Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition).
分子量

744.41

分子式

C34H66ClN11O5
CAS 番号
Appearance

Solid

Color

White to off-white

輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 100 mg/mL (134.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3433 mL 6.7167 mL 13.4335 mL
5 mM 0.2687 mL 1.3433 mL 2.6867 mL
10 mM 0.1343 mL 0.6717 mL 1.3433 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

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体積 （開始）

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3433 mL 6.7167 mL 13.4335 mL 33.5836 mL
5 mM 0.2687 mL 1.3433 mL 2.6867 mL 6.7167 mL
10 mM 0.1343 mL 0.6717 mL 1.3433 mL 3.3584 mL
15 mM 0.0896 mL 0.4478 mL 0.8956 mL 2.2389 mL
20 mM 0.0672 mL 0.3358 mL 0.6717 mL 1.6792 mL
25 mM 0.0537 mL 0.2687 mL 0.5373 mL 1.3433 mL
30 mM 0.0448 mL 0.2239 mL 0.4478 mL 1.1195 mL
40 mM 0.0336 mL 0.1679 mL 0.3358 mL 0.8396 mL
50 mM 0.0269 mL 0.1343 mL 0.2687 mL 0.6717 mL
60 mM 0.0224 mL 0.1119 mL 0.2239 mL 0.5597 mL
80 mM 0.0168 mL 0.0840 mL 0.1679 mL 0.4198 mL
100 mM 0.0134 mL 0.0672 mL 0.1343 mL 0.3358 mL
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Decanoyl-RVKR-CMK Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decanoyl-RVKR-CMK150113-99-8DecRVKRcmkHIVHuman immunodeficiency virusglycoproteinVGF glycoproteinVGFHIV-2 ROD infectionreplicationInhibitorinhibitorinhibit

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製品名:
Decanoyl-RVKR-CMK
製品番号:
HY-107760
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