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estradiol-17-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Bacterial (5) Biochemical Assay Reagents (2) Cytochrome P450 (1) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (5) Environmental Pollutants (1) Estrogen Receptor/ERR (9) Isotope-Labeled Compounds (6) Microtubule/Tubulin (1) Nucleoside Antimetabolite/Analog (1) P-glycoprotein (6) Reference Standards (2) TRP Channel (1)
By Research Areas:	Cancer (9) Endocrinology (8) Infection (4) Metabolic Disease (6)
Click Chemistry:	Alkynes (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0141

*Estradiol* Maximum Cited Publications 122 Publications Verification β-estradiol; E2; 17β-estradiol; 17β-Oestradiol	Estrogen Receptor/ERR Endogenous Metabolite Bacterial	Endocrinology Cancer
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B0216

Ethinylestradiol 5 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol	Environmental Pollutants Endogenous Metabolite Estrogen Receptor/ERR	Endocrinology Cancer
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-B0672

Estradiol valerate β-estradiol 17-valerate	Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-W353102

Estradiol 17-(β-D-Glucuronide)	Endogenous Metabolite P-glycoprotein	Metabolic Disease
Estradiol 17-(β-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) can be used in studies related to intrahepatic cholestasis .

HY-129987

Estradiol 17-(β-D-Glucuronide) sodium	Endogenous Metabolite P-glycoprotein	Metabolic Disease
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) sodium is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) sodium regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) sodium induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) sodium can be used in studies related to intrahepatic cholestasis .

HY-B0216S

*Ethynyl Estradiol-d4* 17α-Ethynylestradiol-d₄; Ethynylestradiol-d₄	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0708

*β-Estradiol 17-acetate* 1 Publications Verification 1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Estrogen Receptor/ERR	Endocrinology
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a long-acting endogenous estrogen precursor and also a cell viability and proliferation enhancer. β-Estradiol 17-acetate promotes the adhesion and proliferation of freshly isolated and revived female-derived human brain microvascular endothelial cells, and reverses the decreased viability of revived male-derived human brain microvascular endothelial cells. β-Estradiol 17-acetate exerts the microvascular protective effect of estrogen, enabling non-tumor human brain microvascular endothelial cells to be cultured in vitro for 2 months after cryopreservation. β-Estradiol 17-acetate is biotransformed into β-estradiol via hydrolase action in the in vitro skin of humans, hairless dogs, rats and hairless mice .

HY-B0947

Sulfanitran 2 Publications Verification	P-glycoprotein Bacterial	Infection
Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .

HY-B0672R

Estradiol valerate (Standard) β-estradiol 17-valerate (Standard)	Reference Standards Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate (Standard) is the analytical standard of Estradiol valerianate. This product is intended for research and analytical applications. Estradiol valerate (β-Estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-148586

*β-Estradiol 17-hemisuccinate*	Drug Derivative	Others
β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol (HY-B0141) .

HY-W008581

Estradiol 3-methyl ether 3-O-Methyl estradiol; 17β-estradiol 3-methyl ether; 3-Methoxyestradiol	Biochemical Assay Reagents TRP Channel Microtubule/Tubulin Autophagy	Metabolic Disease Cancer
Estradiol 3-methyl ether (EDME) is a highly selective TRPML1 ion channel antagonist and microtubule (microtubule) depolymerizing agent, with IC₅₀ values of 0.22 μM and 3.8 μM against TRPML1 and TRPML2, respectively; it shows no activity against TRPML3. Estradiol 3-methyl ether induces the disruption of cytoplasmic microtubule networks in mammalian cells, with an EC₅₀ of 9 μM. Independent of estrogen receptors, Estradiol 3-methyl ether blocks autophagy (autophagy), TFEB nuclear translocation, and inhibits the migration and invasion of triple-negative breast cancer cells by suppressing TRPML1. Estradiol 3-methyl ether is applicable for relevant research on triple-negative breast cancer .

HY-123742

Estradiol 3-sulfate 17-glucuronide potassium	P-glycoprotein	Metabolic Disease
Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a K_i of 22 μM .

HY-W781971

Estradiol 17-Benzoate-13C2	Isotope-Labeled Compounds	Others
Estradiol 17-Benzoate- ¹³C₂ is the ¹³C-labeled Estradiol 17-Benzoate.

HY-142279S

*17β-Estradiol 17-acetate 3-β-D-glucuronide-d3*	Isotope-Labeled Compounds	Others
17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide .

HY-106828

E2-CDS estradiol 17-Dihydrotrigonelline	Estrogen Receptor/ERR	Metabolic Disease
E2-CDS (Estradiol 17-Dihydrotrigonelline) is a redox-based chemical delivery system for estradiol (E2). E2-CDS is capable of sustained and brain-selective delivery of estradiol .

HY-B0672S1

Estradiol valerianate-d4 β-estradiol 17-valerate-d₄	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0947S1

Sulfanitran-13C6	P-glycoprotein Bacterial	Infection
Sulfanitran- ¹³C₆ is the ¹³C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).

HY-B0947S

Sulfanitran-d4	Isotope-Labeled Compounds Bacterial	Infection
Sulfanitran-d₄ is the deuterium labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .

HY-B0947R

Sulfanitran (Standard)	P-glycoprotein Bacterial Reference Standards	Infection
Sulfanitran (Standard) is the analytical standard of Sulfanitran. This product is intended for research and analytical applications. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .

HY-B0672S

Estradiol valerianate-d9	Isotope-Labeled Compounds Estrogen Receptor/ERR	Endocrinology Cancer
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-Z2909

Estradiol impurity 5 estradiol 17-butyrate	Drug Intermediate	Others
Estradiol impurity 5 (Estradiol 17-butyrate) is an impurity of Estradiol.

HY-180679

*2-Methoxy-estradiol-17beta 3-glucuronide*	Nucleoside Antimetabolite/Analog	Metabolic Disease
2-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite.

HY-W777292

*Ethynyl estradiol 17-β-D-glucuronide*	Biochemical Assay Reagents	Others
Ethynyl estradiol 17-β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-180420

Tan-931	Cytochrome P450	Cancer
Tan-931 is a non-competitive and selective inhibitor of aromatase , with an IC₅₀ is 17.2 μM and a K_i of 40 μM for human aromatase, and an IC₅₀ of 162 μM for rat aromatase. Tan-931 reduces plasma estradiol-17β level and weight of ovaries and uterus in PMSG (HY-N12634)-treated female rats. Tan-931 can be used for the research of estrogen-dependent metastatic breast cancer .

HY-W742818

*3-O-Benzyl 17b-Estradiol-d3 17-Acetate*	Isotope-Labeled Compounds	Others
3-O-Benzyl 17b-Estradiol-d₃ 17-Acetate is the deuterium labeled 3-O-Benzyl 17b-Estradiol 17-Acetate.

Cat. No.	Product Name	Type

HY-W777292

*Ethynyl estradiol 17-β-D-glucuronide*	Biochemical Assay Reagents
Ethynyl estradiol 17-β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Ethynyl estradiol 17-β-D-glucuronide

Biochemical Assay Reagents

Ethynyl estradiol 17-β-D-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0141

*Estradiol* Maximum Cited Publications 122 Publications Verification β-estradiol; E2; 17β-estradiol; 17β-Oestradiol	Monophenols Classification of Application Fields Sunscreen Disease markers Phenols Endocrine diseases Cosmetic Research Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering .

HY-B0216

Ethinylestradiol 5 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol	Structural Classification Monophenols Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Environmental Pollutants Endogenous Metabolite Estrogen Receptor/ERR
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-W353102

Estradiol 17-(β-D-Glucuronide)	Structural Classification Monophenols Classification of Application Fields Phenols Metabolic Disease Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite P-glycoprotein
Estradiol 17-(β-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) can be used in studies related to intrahepatic cholestasis .

HY-129987

Estradiol 17-(β-D-Glucuronide) sodium	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite P-glycoprotein
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) sodium is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) sodium regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) sodium induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) sodium can be used in studies related to intrahepatic cholestasis .

HY-B0708

*β-Estradiol 17-acetate* 1 Publications Verification 1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Structural Classification Monophenols Animals Classification of Application Fields Phenols Disease Research Fields Endocrinology Steroids Source Classification	Estrogen Receptor/ERR
β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a long-acting endogenous estrogen precursor and also a cell viability and proliferation enhancer. β-Estradiol 17-acetate promotes the adhesion and proliferation of freshly isolated and revived female-derived human brain microvascular endothelial cells, and reverses the decreased viability of revived male-derived human brain microvascular endothelial cells. β-Estradiol 17-acetate exerts the microvascular protective effect of estrogen, enabling non-tumor human brain microvascular endothelial cells to be cultured in vitro for 2 months after cryopreservation. β-Estradiol 17-acetate is biotransformed into β-estradiol via hydrolase action in the in vitro skin of humans, hairless dogs, rats and hairless mice .

HY-180679

*2-Methoxy-estradiol-17beta 3-glucuronide*	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
2-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite.

HY-180420

Tan-931	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Cytochrome P450
Tan-931 is a non-competitive and selective inhibitor of aromatase , with an IC₅₀ is 17.2 μM and a K_i of 40 μM for human aromatase, and an IC₅₀ of 162 μM for rat aromatase. Tan-931 reduces plasma estradiol-17β level and weight of ovaries and uterus in PMSG (HY-N12634)-treated female rats. Tan-931 can be used for the research of estrogen-dependent metastatic breast cancer .

Cat. No.	Product Name	Chemical Structure

HY-B0216S

*Ethynyl Estradiol-d4*
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Ethynyl Estradiol-d4

Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W781971

Estradiol 17-Benzoate-13C2
Estradiol 17-Benzoate- ¹³C₂ is the ¹³C-labeled Estradiol 17-Benzoate.

HY-142279S

*17β-Estradiol 17-acetate 3-β-D-glucuronide-d3*
17β-Estradiol 17-acetate 3-β-D-glucuronide-d₃ is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide .

HY-B0672S1

Estradiol valerianate-d4
Estradiol valerianate-d₄ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-B0947S1

Sulfanitran-13C6
Sulfanitran- ¹³C₆ is the ¹³C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).

HY-B0947S

Sulfanitran-d4
Sulfanitran-d₄ is the deuterium labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .

HY-B0672S

Estradiol valerianate-d9
Estradiol valerianate-d₉ is the deuterium labeled Estradiol valerianate. Estradiol valerianate (β-estradiol 17-valerate) is a synthetic estrogen widely used in combination with other steroid hormones in hormone replacement therapy agents.

HY-W742818

*3-O-Benzyl 17b-Estradiol-d3 17-Acetate*
3-O-Benzyl 17b-Estradiol-d₃ 17-Acetate is the deuterium labeled 3-O-Benzyl 17b-Estradiol 17-Acetate.

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HY-P83688

	Estradiol Antibody Beta-estradiol, 17beta-estradiol, estrace, oestradiol, dihydrofolliculin, progynon, dihydroxyestrin, dihydrotheelin, diogynets	ELISA	Species independent
	Estradiol Antibody is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Estradiol.

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HY-B0216

Ethinylestradiol 5 Publications Verification Ethynyl estradiol; 17α-Ethynylestradiol		Alkynes
Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers .

HY-B0216S

*Ethynyl Estradiol-d4* 17α-Ethynylestradiol-d₄; Ethynylestradiol-d₄		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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