2. Others Immunology/Inflammation Apoptosis
  3. MOFs NO Synthase Apoptosis
  4. FeTPPS

FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process.

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FeTPPS

FeTPPS Estructura química

No. CAS : 90384-82-0

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

FeTPPS Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE FeTPPS

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Descripciòn

FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage[1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process[2].

In Vitro

FeTPPS acts as an effective pro-oxidant towards appreciable substrates in vitro in the presence of oxidant. FeTPPS protects cells against oxidative damage induced by H2O2, generated by Glucose (G)-glucose oxidase (GO) system[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FeTPPS Related Antibodies

Cell Viability Assay[2]

Cell Line: Human hepatocellular carcinoma (HepG2)
Concentration: 5, 10, 15, 20, 25 μM
Incubation Time: Treated 12 h before being exposed to H2O2
Result: Could protect cells against oxidative damage induced by H2O2.
Peso molecular

1024.27

Fòrmula

C44H28ClFeN4O12S4
No. CAS
Appearance

Solid

Color

Brown to black

SMILES

O=S([O-])(C1=CC=C(C(C(C=C2)=[N]3C2=C(C4=CC=C5C(C6=CC=C(S(=O)([O-])=O)C=C6)=C7C=C8)C9=CC=C(S(=O)([O-])=O)C=C9)=C%10C=CC%11=C(C%12=CC=C(S(=O)([O-])=O)C=C%12)C8=[N]7[Fe+3]3([Cl-])([N-]45)[N-]%10%11)C=C1)=O.[4H+]
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

H2O : 5 mg/mL (4.88 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9763 mL 4.8815 mL 9.7631 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Pureza y Documentación

Purity: 99.9%

SDS (251 KB)

COA (265 KB) MS (227 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.9763 mL 4.8815 mL 9.7631 mL 24.4076 mL
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FeTPPS Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FeTPPS90384-82-0MOFsNO SynthaseApoptosisMetal-Organic FrameworksNitric oxide synthasesNOSHemePro-oxidativeactivity,reactiveoxygenspeciesperoxynitritecorticalimpactinflammationapoptosisInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
FeTPPS
Cat. No.:
HY-131697
Cantidad:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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