2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. GDP-L-fucose

GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats.

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GDP-L-fucose

GDP-L-fucose Chemische Struktur

CAS. Nr. : 15839-70-0

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10 mM * 1 mL in Water
ready for reconstitution
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Other Forms of GDP-L-fucose:

GDP-L-fucose Related Antibodies

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Beschreibung

GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats[1][2].
IC50 & Target

Human Endogenous Metabolite

 

In Vivo

GDP-L-fucose is associated with diabetes in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molekulargewicht

589.34

Formel

C16H25N5O15P2
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(O)(OP(O)(O[C@@H]4[C@@H](O)[C@H](O)[C@H](O)[C@H](C)O4)=O)=O)O3)=C2N=C(N)N1
Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Lösungsmittel & Löslichkeit
In Vitro: 

H2O : 100 mg/mL (169.68 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6968 mL 8.4841 mL 16.9681 mL
5 mM 0.3394 mL 1.6968 mL 3.3936 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Reinheit & Dokumentation

Purity: 99.82%

SDS (393 KB)

COA (250 KB) HNMR (284 KB) RP-HPLC (205 KB) LCMS (96 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6968 mL 8.4841 mL 16.9681 mL 42.4203 mL
5 mM 0.3394 mL 1.6968 mL 3.3936 mL 8.4841 mL
10 mM 0.1697 mL 0.8484 mL 1.6968 mL 4.2420 mL
15 mM 0.1131 mL 0.5656 mL 1.1312 mL 2.8280 mL
20 mM 0.0848 mL 0.4242 mL 0.8484 mL 2.1210 mL
25 mM 0.0679 mL 0.3394 mL 0.6787 mL 1.6968 mL
30 mM 0.0566 mL 0.2828 mL 0.5656 mL 1.4140 mL
40 mM 0.0424 mL 0.2121 mL 0.4242 mL 1.0605 mL
50 mM 0.0339 mL 0.1697 mL 0.3394 mL 0.8484 mL
60 mM 0.0283 mL 0.1414 mL 0.2828 mL 0.7070 mL
80 mM 0.0212 mL 0.1061 mL 0.2121 mL 0.5303 mL
100 mM 0.0170 mL 0.0848 mL 0.1697 mL 0.4242 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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GDP-L-fucose Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GDP-L-fucose15839-70-0Endogenous Metabolitenucleotide sugarsubstratefucose oligosaccharideInhibitorinhibitorinhibit

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