2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Gilvetmab

Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. Gilvetmab blocks the interaction between PD-1 and its ligand PD-L1/L2. Gilvetmab can be used in malignant melanoma and mast cell tumor research.

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CAS. Nr. : 1808081-43-7

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Gilvetmab Related Antibodies

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Beschreibung

Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. Gilvetmab blocks the interaction between PD-1 and its ligand PD-L1/L2. Gilvetmab can be used in malignant melanoma and mast cell tumor research[1][2][3].

Isotype

Canis IgG2 kappa
Species Reactivity

Canlupfam
IC50 & Target

Canlupfam PDCD1
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molekulargewicht

147.71 kDa

CAS. Nr.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Gilvetmab]
Versand

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • IgG2-kappa
Biological Activity
  • Immobilized PD-1 Protein,Canine (HEK293, C-His, HYP73342A) can bind Gilvetmab. The EC50 for this effect is 287 ng/mL.
Reinheit & Dokumentation

Purity: 99.37%

SDS (251 KB)

COA (232 KB) SDS-PAGE (83 KB) SEC-HPLC (164 KB)

Inhibitory Antibodies User Guide (603 KB)
Verweise
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Gilvetmab Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gilvetmab1808081-43-7PD-1/PD-L1PD-1/Programmed death-ligand 1malignant melanomaInhibitorinhibitorinhibit

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HY-P99641
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SAFETY DATA SHEET (SDS)

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