1808081-43-7
1808081-43-7
Chemical Structure
Biological Activity: Gilvetmab is a canine-derived anti-cPD-1 monoclonal antibody, as well as an immune activator/antitumor agent. Gilvetmab binds to canine PD-1, blocks the interaction of PD-1/PD-L1/L2, prevents immunosuppression, reactivates antitumor responses, induces tumor regression or disease stabilization, and may also trigger pseudoprogression. Gilvetmab can be used in research related to malignant melanoma and mast cell tumors[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gilvetmab | 99.37% | Gilvetmab is a canine-derived anti-cPD-1 monoclonal antibody, as well as an immune activator/antitumor agent. Gilvetmab binds to canine PD-1, blocks the interaction of PD-1/PD-L1/L2, prevents immunosuppression, reactivates antitumor responses, induces tumor regression or disease stabilization, and may also trigger pseudoprogression. Gilvetmab can be used in research related to malignant melanoma and mast cell tumors. | ||||||||||||||||||||
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References
- [1]. Magee K, et al. Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting. PloS one. 2021;16(8):e0255798. [Content Brief]
- [2]. Xia YY, et al. Limited Clinical Efficacy with Potential Adverse Events in a Pilot Study of Autologous Adoptive Cell Therapy in Canine Oral Malignant Melanoma. Veterinary sciences. 2024 Mar 28;11(4):150. [Content Brief]
- [3]. Wang J, et al. Current Review of Monoclonal Antibody Therapeutics in Small Animal Medicine. Animals : an open access journal from MDPI. 2025 Feb 07;15(4):472. [Content Brief]
- [4]. Chon E, et al. Efficacy and safety evaluation of gilvetmab in dogs with melanoma and mast cell tumor. Journal of veterinary internal medicine. 2026 May 04;40(3):aalag098. [Content Brief]
Keywords
