Gilvetmab
Based on 1 Customer Validation
Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. Gilvetmab blocks the interaction between PD-1 and its ligand PD-L1/L2. Gilvetmab can be used in malignant melanoma and mast cell tumor research.
For research use only. We do not sell to patients.
- Purity: 99.37%
- CAS No.: 1808081-43-7
- Molecular Weight:147.71 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Canis IgG2 kappa
Canlupfam
Canlupfam PDCD1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG2-kappa
ELISA, FACS, Functional assay
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Immobilized PD-1 Protein,Canine (HEK293, C-His, HYP73342A) can bind Gilvetmab. The EC50 for this effect is 287 ng/mL.
Chemical Information
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CAS No. 1808081-43-7
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Appearance Liquid
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Molecular Weight 147.71 kDa
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Color Colorless to light yellow
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SMILES
[Gilvetmab]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Magee K, et al. Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting. PLoS One. 2021 Aug 12;16(8):e0255798. [Content Brief]
[2]. Xia YY, et al. Limited Clinical Efficacy with Potential Adverse Events in a Pilot Study of Autologous Adoptive Cell Therapy in Canine Oral Malignant Melanoma. Vet Sci. 2024 Mar 28;11(4):150. [Content Brief]
[3]. Wang J, et al. Current Review of Monoclonal Antibody Therapeutics in Small Animal Medicine. Animals (Basel). 2025 Feb 7;15(4):472. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)