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Tislelizumab

(Synonyms: BGB-A317)
3 Cited Publications
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Based on 3 publication(s) in Google Scholar

Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma.

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  • Pureté: 98.10%
  • CAS No.: 1858168-59-8
  • Masse moléculaire:145 kDa
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tislelizumab
  • Experimental Validation Results for Tislelizumab
  • Experimental Validation Results for Tislelizumab
  • Tislelizumab Chemical Structure
    Tislelizumab Chemical Structure
CAS No.: 1858168-59-8
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Tislelizumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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    Human IgG4 kappa

  • 1/16

    Flow cytometry analysis of PD-1 overexpression Jurkat cells labelling PD-1 with Tislelizumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).

  • 1/16

    Tislelizumab purchased from MedChemExpress. Usage Cited in: Cancer Cell Int. 2024 Jun 29;24(1):225. [Abstract]

    Customer Validation
     Tislelizumab (50 µg/mL; 24 h). IFN-γ concentration in the supernatant of co-cultured cell lines was assessed by ELISA.

  • Tislelizumab Chemical Structure
    1/16
  • Tislelizumab
  • Flow cytometry analysis of PD-1 overexpression Jurkat cells labelling PD-1 with Tislelizumab at 20 nM (Red). Goat anti human IgG Fc (Alexa Fluor488) was used as the secondary antibody at 1/1000 dilution. Isotype control - human IgG (Blue). Unlabeled control - Unlabelled cells (Gray).