Glycodeoxycholic acid-d₆

Name: Glycodeoxycholic acid-d 6
Brand: MedChemExpress
SKU: HY-125731S1
Rating: 4.5 (0 reviews)

Cat. No.: HY-125731S1 Purity: 99.91%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Glycodeoxycholic acid-d₆ is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.

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Glycodeoxycholic acid-d₆ 화학구조

CAS No. : 2483831-98-5

사이즈	재고	수량
1 mg	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
5 mg	견적 받기
10 mg	견적 받기

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of Glycodeoxycholic acid-d₆:

Glycodeoxycholic acid In-stock

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Human Endogenous Metabolite Microbial Metabolite

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Glycodeoxycholic acid-d₆ is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

455.66

화학식

C₂₆H₃₇D₆NO₅

CAS No.

2483831-98-5

Unlabeled CAS

360-65-6

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCC(O)=O)=O)([H])[C@@]3([H])[C@@](C([2H])([2H])[C@@H]1O)([H])[C@@]4([C@](C([2H])([2H])[C@@H](C([2H])([2H])C4)O)([H])CC3)C

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 125 mg/mL (274.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1946 mL	10.9731 mL	21.9462 mL
5 mM	0.4389 mL	2.1946 mL	4.3892 mL
10 mM	0.2195 mL	1.0973 mL	2.1946 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.91%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (251 KB) RP-HPLC (211 KB) MS (149 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1946 mL	10.9731 mL	21.9462 mL	54.8655 mL
	5 mM	0.4389 mL	2.1946 mL	4.3892 mL	10.9731 mL
	10 mM	0.2195 mL	1.0973 mL	2.1946 mL	5.4865 mL
	15 mM	0.1463 mL	0.7315 mL	1.4631 mL	3.6577 mL
	20 mM	0.1097 mL	0.5487 mL	1.0973 mL	2.7433 mL
	25 mM	0.0878 mL	0.4389 mL	0.8778 mL	2.1946 mL
	30 mM	0.0732 mL	0.3658 mL	0.7315 mL	1.8288 mL
	40 mM	0.0549 mL	0.2743 mL	0.5487 mL	1.3716 mL
	50 mM	0.0439 mL	0.2195 mL	0.4389 mL	1.0973 mL
	60 mM	0.0366 mL	0.1829 mL	0.3658 mL	0.9144 mL
	80 mM	0.0274 mL	0.1372 mL	0.2743 mL	0.6858 mL
	100 mM	0.0219 mL	0.1097 mL	0.2195 mL	0.5487 mL