2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. hCAIX-IN-19

hCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI ) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117).

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hCAIX-IN-19

hCAIX-IN-19 화학구조

사이즈 재고
50 mg   견적 받기  
100 mg   견적 받기  
250 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

hCAIX-IN-19 Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

View All Isoforms
CA CA I CA Ⅱ CA IX CA XII CA VII CA VI CA VA CA VB CA XIII CA XIV

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

hCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI ) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117)[1].

IC50 & Target

hCA IX

6.2 nM (Ki)

In Vitro

hCAIX-IN-19 (1.0-100.0 μM, 48 h ) shows antiproliferative activity in U87MG cells, MDA-MB-231 cells and PANC-1 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

hCAIX-IN-19 Related Antibodies

Cell Proliferation Assay[1]

Cell Line: U87MG cells, MDA-MB-231 cells, PANC-1 cells
Concentration: 1.0 μM, 3.0 μM, 10.0 μM, 30.0 μM, 100.0 μM
Incubation Time: 48 h
Result: Obviously affected cell proliferation at 100 μM in U87MG cells.
Reduced cell proliferation to 39% at the highest dose tested in MDA-MB-231 cells.
분자량

566.73

화학식

C29H34N4O4S2
SMILES

O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(N(CC3=CC=C(C=CC=C4)C4=C3)CCC5=CC=C(S(=O)(N)=O)C=C5)=O)([H])N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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hCAIX-IN-19 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hCAIX-IN-19Carbonic AnhydraseCarbonate dehydratasehCAIX-IN-19 (1.0-100.0 μM48h ) shows antiproliferative activity in U87MG cellsMDA-MB-231 cells and PANC-1 cells[1].Inhibitorinhibitorinhibit

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상품명:
hCAIX-IN-19
Cat. No.:
HY-157135
수량:
MCE Japan Authorized Agent:

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