Hypoxanthine-¹³C₅,¹⁵N₄  (Synonyms: Purin-6-ol-¹³C₅,¹⁵N₄; Sarcine-¹³C₅,¹⁵N₄)

Hypoxanthine-¹³C₅,¹⁵N4 is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

145.05

¹³C₅H₄¹⁵N₄O

1987883-25-9

68-94-0

Solid

White to light yellow

O=[13C]1[13C]2=[13C]([15N]=[13CH][15NH]2)[15NH][13CH]=[15N]1

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-245.  [Content Brief]