2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs) Transmembrane Glycoprotein
  4. Litifilimab

Litifilimab  (Synonyms: BIIB059)

Cat. No.: HY-P9990 Pureza: 99.51%
COA
SDS
Technical Support

Litifilimab (BIIB059) is a humanized anti-BDCA2 IgG1 monoclonal antibody administered subcutaneously. Litifilimab can inhibit the production of type I interferons, cytokines and chemokines. Litifilimab can be used in the research of diseases such as systemic lupus erythematosus.

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No. CAS : 2407378-48-5

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Litifilimab Recomendaciones destacadas:

Litifilimab Related Antibodies

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Descripciòn

Litifilimab (BIIB059) is a humanized anti-BDCA2 IgG1 monoclonal antibody administered subcutaneously. Litifilimab can inhibit the production of type I interferons, cytokines and chemokines. Litifilimab can be used in the research of diseases such as systemic lupus erythematosus[1][2].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
IC50 & Target

CLEC4C
Ensayo clínico
Gene ID

170482  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Peso molecular

146.6 kDa

No. CAS
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Litifilimab]
Envío

Shipping with dry ice.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized CLEC4C Protein, Human can bind Litifilimab. The EC50 for this effect is 19.73 ng/mL.
Pureza y Documentación

Purity: 99.51%

SDS (251 KB)

COA (232 KB) SDS-PAGE (80 KB) SEC-HPLC (138 KB)

Inhibitory Antibodies User Guide (603 KB)
Referencias
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Litifilimab Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Litifilimab2407378-48-5BIIB059BIIB 059BIIB-059C-type Lectin-like Receptors (CTLRs)Transmembrane GlycoproteinhumanizedIgG1-κ antibodyBDCA2Inhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Litifilimab
Cat. No.:
HY-P9990
Cantidad:
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