2407378-48-5
2407378-48-5
Chemical Structure
Litifilimab
Synonym(s): BIIB059
- CAS No.: 2407378-48-5
- Formula:N/A
- Molecular Weight:(146.6 kDa)
IUPAC Name: tris(methyl-d3)sulfonium (phosphonomethyl)glycinate
SMILES: [Litifilimab]
Biological Activity: Litifilimab (BIIB059) is a humanized IgG1 monoclonal antibody targeting BDCA2. Litifilimab induces internalization of BDCA2 receptors on the membrane of plasmacytoid dendritic cells, inhibits the TLR7/TLR9 signaling pathway, and suppresses the production of type I interferons. Litifilimab can be used in the research of systemic and cutaneous lupus erythematosus[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Litifilimab | 99.51% | Litifilimab (BIIB059) is a humanized IgG1 monoclonal antibody targeting BDCA2. Litifilimab induces internalization of BDCA2 receptors on the membrane of plasmacytoid dendritic cells, inhibits the TLR7/TLR9 signaling pathway, and suppresses the production of type I interferons. Litifilimab can be used in the research of systemic and cutaneous lupus erythematosus. | ||||||||||||||||||||
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