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  3. Lobetyolinin

Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research.

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Lobetyolinin

Lobetyolinin 構造式

CAS 番号 : 142451-48-7

容量 価格(税別) 在庫状況 数量
5 mg $350 在庫あり
10 mg $525 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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  • 生物活性

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製品説明

Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research[1][2].

体外実験

Lobetyolinin (50 µM; 24 h) significantly restores the heart rate of larvae and improves atrioventricular block in Terfenadine (HY-B1193)-induced arrhythmia model of Cmlc2-GFP transgenic zebrafish larvae[1].
Lobetyolinin (6 h) restores abnormal heart rate and rhythm in adult zebrafish model[1].
Lobetyolinin (up to 80 µM) shows no significant inhibitory effect on cell viability and does not induce apoptosis in HepG2 and Huh7 hepatocellular carcinoma cell models[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

558.57

分子式

C26H38O13

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

C/C=C/C#CC#C[C@@H](O)[C@@H](/C=C/CCCO)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO

Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度
体外: 

Ethanol : 6.67 mg/mL (11.94 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7903 mL 8.9514 mL 17.9029 mL
5 mM 0.3581 mL 1.7903 mL 3.5806 mL
10 mM 0.1790 mL 0.8951 mL 1.7903 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

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体積 (開始)

V1

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濃度 (終了)

C2

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体積 (終了)

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In Vivo Dissolution Calculator
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純度とドキュメンテーション

純度: 99.06%

参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.7903 mL 8.9514 mL 17.9029 mL 44.7571 mL
5 mM 0.3581 mL 1.7903 mL 3.5806 mL 8.9514 mL
10 mM 0.1790 mL 0.8951 mL 1.7903 mL 4.4757 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
Lobetyolinin
製品番号:
HY-124031
数量:
MCE 日本正規代理店: