2. Anti-infection
  3. Bacterial
  4. Methenamine hippurate

Methenamine hippurate  (Synonyms: Hexamine hippurate)

Cat. No.: HY-B1691 Pureza: 99.55%
COA
SDS
Instrucciones de manejo Technical Support

Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens.

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Methenamine hippurate

Methenamine hippurate Estructura química

No. CAS : 5714-73-8

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
100 mg En stock
250 mg En stock
500 mg   Obtener un presupuesto  
1 g   Obtener un presupuesto  

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Other Forms of Methenamine hippurate:

Methenamine hippurate Related Antibodies

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Descripciòn

Methenamine hippurate (Hexamine hippurate) is an orally active urinary antiseptic agent with a wide antibacterial spectrum. Methenamine hippurate is effective against most common urinary tract pathogens[1][2].

In Vitro

Methenamine hippurate is a urinary antibacterial agent which releases formaldehyde and is excreted in the urine. Methenamine hippurate has a demonstrable activity in vitro at pH 5 to 6 against Escherichia coli, Staphylococcus aureus, Aerobacter aeroaenes, Pseudomonas aeruginosa and Proteus vulgaris, and a wide range of action against Klebsiella pneumoniae, Ps. aeruginosa, E. coli, Staph. aureus and Streptococcus haemolytic at pH of 7.4. This action is more effective than that of Methenamine alone, of Hippuric acid alone or of Sulphadiazine[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Methenamine hippurate Related Antibodies
Ensayo clínico
Peso molecular

319.36

Fòrmula

C15H21N5O3
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CNC(C1=CC=CC=C1)=O.N2(C3)CN4CN3CN(C4)C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad
In Vitro: 

H2O : 100 mg/mL (313.13 mM; Need ultrasonic)

DMSO : 25 mg/mL (78.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1313 mL 15.6563 mL 31.3126 mL
5 mM 0.6263 mL 3.1313 mL 6.2625 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (313.13 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 99.55%

SDS (393 KB)

COA (254 KB) HNMR (239 KB) LCMS (132 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.1313 mL 15.6563 mL 31.3126 mL 78.2816 mL
5 mM 0.6263 mL 3.1313 mL 6.2625 mL 15.6563 mL
10 mM 0.3131 mL 1.5656 mL 3.1313 mL 7.8282 mL
15 mM 0.2088 mL 1.0438 mL 2.0875 mL 5.2188 mL
20 mM 0.1566 mL 0.7828 mL 1.5656 mL 3.9141 mL
25 mM 0.1253 mL 0.6263 mL 1.2525 mL 3.1313 mL
30 mM 0.1044 mL 0.5219 mL 1.0438 mL 2.6094 mL
40 mM 0.0783 mL 0.3914 mL 0.7828 mL 1.9570 mL
50 mM 0.0626 mL 0.3131 mL 0.6263 mL 1.5656 mL
60 mM 0.0522 mL 0.2609 mL 0.5219 mL 1.3047 mL
H2O 80 mM 0.0391 mL 0.1957 mL 0.3914 mL 0.9785 mL
100 mM 0.0313 mL 0.1566 mL 0.3131 mL 0.7828 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Methenamine hippurate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methenamine5714-73-8HexamineBacterialurinaryantiseptictractpathogensbacterialurineInhibitorinhibitorinhibit

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Nombre del producto:
Methenamine hippurate
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HY-B1691
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