1. Anti-infection
  2. Bacterial Fungal
  3. Monocerin

Monocerin is an isocoumarin derivative. Monocerin is isolated from Microdochium bolleyi, an endophytic fungus from Fagonia cretica. Monocerin shows good antifungal, antibacterial, and antialgal activities against Microbotryum violaceum, Escherichia coli, Bacillus megaterium, and Chlorella fusca.

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Monocerin

Monocerin Estructura química

No. CAS : 30270-60-1

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Descripciòn

Monocerin is an isocoumarin derivative. Monocerin is isolated from Microdochium bolleyi, an endophytic fungus from Fagonia cretica. Monocerin shows good antifungal, antibacterial, and antialgal activities against Microbotryum violaceum, Escherichia coli, Bacillus megaterium, and Chlorella fusca[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
>162.1 μM
Compound: 1
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
[PMID: 21174408]
HepG2 IC50
>162.1 μM
Compound: 1
Cytotoxicity against human HepG2 cells by MTT assay
Cytotoxicity against human HepG2 cells by MTT assay
[PMID: 21174408]
HL-60 IC50
>130 μM
Compound: 1
Antioxidant activity in human HL60 cells assessed as inhibition of TPA-induced superoxide anion radical production
Antioxidant activity in human HL60 cells assessed as inhibition of TPA-induced superoxide anion radical production
[PMID: 21174408]
HuCC-A1 IC50
>162.1 μM
Compound: 1
Cytotoxicity against human HuCCA1 cells by MTT assay
Cytotoxicity against human HuCCA1 cells by MTT assay
[PMID: 21174408]
MOLT-3 IC50
153 μM
Compound: 1
Cytotoxicity against human MOLT3 cells by XTT assay
Cytotoxicity against human MOLT3 cells by XTT assay
[PMID: 21174408]
Vero CC50
87.5 μM
Compound: 1
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability by MTT assay
[PMID: 33979168]
Peso molecular

308.33

Fòrmula

C16H20O6

No. CAS
SMILES

O=C1C2=C(O)C(OC)=C(OC)C=C2[C@](O[C@@H](CCC)C3)([H])[C@]3([H])O1

Structure Classification
Initial Source

Drechslera sp. strain 678

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Monocerin
Cat. No.:
HY-N6294
Cantidad:
MCE Japan Authorized Agent: