N-Dodecyl-β-D-maltoside-d₂₅  (Synonyms: Lauryl Maltoside-d₂₅)

N-Dodecyl-β-D-maltoside-d₂₅ (Lauryl Maltoside-d₂₅) is deuterium labeled N-Dodecyl-β-D-maltoside (HY-128974). N-Dodecyl-β-D-maltoside is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions^[1][2][3][4].

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

535.77

C₂₄H₂₁D₂₅O₁₁

849110-74-3

69227-93-6

Solid

White to off-white

OC[C@@H](O[C@H]([C@@H]([C@H]1O)O)OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO

Room temperature in continental US; may vary elsewhere.

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Tandon S, et al. The effects of lauryl maltoside on the reactivation of several enzymes after treatment with guanidinium chloride. Biochim Biophys Acta. 1988 Jun 29;955(1):19-25.  [Content Brief]

  [2]. Zhang L, et al.Adsorption ofn-Dodecyl-β-d-maltoside on Solids[J].J Colloid Interface, 1997, 256(1):202-208.

  [3]. Kendall-Tobias MW, et al. A rapid procedure for the isolation and purification of photosynthetic reaction centers from Rhodopseudomonas sphaeroides R-26. Arch Biochem Biophys. 1982 Jun;216(1):255-8.  [Content Brief]

  [4]. Zahid NI, et al. Evidence of Increased Hydrophobicity and Dynamics inside the Tail Region of Glycolipid Self-Assemblies Using 2-n-Alkyl-Pyrene Derivatives to Probe Different Locations. Langmuir. 2019 Jul 23;35(29):9584-9592.  [Content Brief]