N-Dodecyl-β-D-maltoside
Based on 6 publication(s) in Google Scholar
N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 69227-93-6
- Formula: C24H46O11
- Molecular Weight:510.62
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) N-Dodecyl-β-D-maltoside
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All DNA/RNA Synthesis Isoforms
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Biological Activity
N-Dodecyl-β-D-maltosid (0.02-10 mg/mL; 90 min) can promote the reactivation of denatured adenosine deaminase, 3-phosphoglycerol phosphokinase, myokinase and 3-hydroxysteroid dehydrogenase in the denatured enzyme dilutive solution (The enzyme activity reaches the maximum at 0.06 mg/mL, and the enzyme activity reaches 98%), but doesn’t significantly reactivate phosphoglucomutase[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 69227-93-6
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Appearance Solid
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Molecular Weight 510.62
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Formula C24H46O11
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Color White to off-white
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SMILES
OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@]1([H])O[C@@H]2[C@H](O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@H]2O)CO
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Synonyms
Lauryl Maltoside
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (6)
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Journal Impact Factor
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Most Recent
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Cell
Two distinct causes contribute to the low efficiency of human pre-implantation development. [Abstract]2026 Jun 11:S0092-8674(26)00637-9. PMID: 42276044 -
Adv Mater
2025 Apr;37(17):e2416349. PMID: 40025988 -
Nat Commun
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition. [Abstract]2024 Jul 23;15(1):6209. PMID: 39043703 -
Mol Cell
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis. [Abstract]2022 May 19;82(10):1821-1835.e6. PMID: 35381197 -
EMBO J
RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis. [Abstract]2025 Aug 26. PMID: 40859035
N-Dodecyl-β-D-maltoside purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Aug 26. [Abstract]
BNE and immunoblotting analysis of DDM (2 mg/mg protein)-solubilised mitochondrial membranes from WT and RTN4IP1KO U2OS lines using antibodies against complexes I (NDUFV1), II (SDHA, loading control) and V (ATP5A).
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iScience
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1. [Abstract]2023 Jul 23;26(8):107446. PMID: 37599822
Solvent & Solubility
H2O : 50 mg/mL (97.92 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (195.84 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Purity & Documentation
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Data Sheet (272 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Tandon S, et al. The effects of lauryl maltoside on the reactivation of several enzymes after treatment with guanidinium chloride. Biochim Biophys Acta. 1988 Jun 29;955(1):19-25. [Content Brief]
[3]. Kendall-Tobias MW, et al. A rapid procedure for the isolation and purification of photosynthetic reaction centers from Rhodopseudomonas sphaeroides R-26. Arch Biochem Biophys. 1982 Jun;216(1):255-8. [Content Brief]
[4]. Zahid NI, et al. Evidence of Increased Hydrophobicity and Dynamics inside the Tail Region of Glycolipid Self-Assemblies Using 2-n-Alkyl-Pyrene Derivatives to Probe Different Locations. Langmuir. 2019 Jul 23;35(29):9584-9592. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.9584 mL | 9.7920 mL | 19.5840 mL | 48.9601 mL |
| 5 mM | 0.3917 mL | 1.9584 mL | 3.9168 mL | 9.7920 mL | |
| 10 mM | 0.1958 mL | 0.9792 mL | 1.9584 mL | 4.8960 mL | |
| 15 mM | 0.1306 mL | 0.6528 mL | 1.3056 mL | 3.2640 mL | |
| 20 mM | 0.0979 mL | 0.4896 mL | 0.9792 mL | 2.4480 mL | |
| 25 mM | 0.0783 mL | 0.3917 mL | 0.7834 mL | 1.9584 mL | |
| 30 mM | 0.0653 mL | 0.3264 mL | 0.6528 mL | 1.6320 mL | |
| 40 mM | 0.0490 mL | 0.2448 mL | 0.4896 mL | 1.2240 mL | |
| 50 mM | 0.0392 mL | 0.1958 mL | 0.3917 mL | 0.9792 mL | |
| 60 mM | 0.0326 mL | 0.1632 mL | 0.3264 mL | 0.8160 mL | |
| 80 mM | 0.0245 mL | 0.1224 mL | 0.2448 mL | 0.6120 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
N-Dodecyl-β-D-maltoside Related Classifications
HY-128974 Related Classifications
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