N-Dodecyl-β-D-maltoside (Synonyms: Lauryl Maltoside)

Name: N-Dodecyl-β-D-maltoside
Brand: MedChemExpress
SKU: HY-128974
Rating: 5.0 (5 reviews)

Cat. No.: HY-128974 Purity: 99.97%: Data Sheet
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Handling Instructions
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N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions.

For research use only. We do not sell to patients.

CAS No. : 69227-93-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	In-stock	Estimated Time of Arrival: December 31
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
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50 g	Get quote

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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of N-Dodecyl-β-D-maltoside:

N-Dodecyl-β-D-maltoside-d₂₅ In-stock

5 Publications Citing Use of MCE N-Dodecyl-β-D-maltoside

: N-Dodecyl-β-D-maltoside purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 Aug 26. [Abstract]; BNE and immunoblotting analysis of DDM (2 mg/mg protein)-solubilised mitochondrial membranes from WT and RTN4IP1KO U2OS lines using antibodies against complexes I (NDUFV1), II (SDHA, loading control) and V (ATP5A).

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Description

In Vitro

N-Dodecyl-β-D-maltosid (0.02-10 mg/mL; 90 min) can promote the reactivation of denatured adenosine deaminase, 3-phosphoglycerol phosphokinase, myokinase and 3-hydroxysteroid dehydrogenase in the denatured enzyme dilutive solution (The enzyme activity reaches the maximum at 0.06 mg/mL, and the enzyme activity reaches 98%), but doesn’t significantly reactivate phosphoglucomutase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

510.62

Formula

C₂₄H₄₆O₁₁

CAS No.

69227-93-6

Appearance

Solid

Color

White to off-white

SMILES

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@]1([H])O[C@@H]2[C@H](O[C@@H](OCCCCCCCCCCCC)[C@H](O)[C@H]2O)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (97.92 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9584 mL	9.7920 mL	19.5840 mL
5 mM	0.3917 mL	1.9584 mL	3.9168 mL
10 mM	0.1958 mL	0.9792 mL	1.9584 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (195.84 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.97%

Select Batch:

Data Sheet (272 KB) SDS (396 KB)

COA (245 KB) HNMR (303 KB) RP-HPLC (217 KB)

Handling Instructions (2659 KB)

References

[1]. Tandon S, et al. The effects of lauryl maltoside on the reactivation of several enzymes after treatment with guanidinium chloride. Biochim Biophys Acta. 1988 Jun 29;955(1):19-25. [Content Brief]

[2]. Zhang L, et al.Adsorption ofn-Dodecyl-β-d-maltoside on Solids[J].J Colloid Interface, 1997, 256(1):202-208.

[3]. Kendall-Tobias MW, et al. A rapid procedure for the isolation and purification of photosynthetic reaction centers from Rhodopseudomonas sphaeroides R-26. Arch Biochem Biophys. 1982 Jun;216(1):255-8. [Content Brief]

[4]. Zahid NI, et al. Evidence of Increased Hydrophobicity and Dynamics inside the Tail Region of Glycolipid Self-Assemblies Using 2-n-Alkyl-Pyrene Derivatives to Probe Different Locations. Langmuir. 2019 Jul 23;35(29):9584-9592. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9584 mL	9.7920 mL	19.5840 mL	48.9601 mL
	5 mM	0.3917 mL	1.9584 mL	3.9168 mL	9.7920 mL
	10 mM	0.1958 mL	0.9792 mL	1.9584 mL	4.8960 mL
	15 mM	0.1306 mL	0.6528 mL	1.3056 mL	3.2640 mL
	20 mM	0.0979 mL	0.4896 mL	0.9792 mL	2.4480 mL
	25 mM	0.0783 mL	0.3917 mL	0.7834 mL	1.9584 mL
	30 mM	0.0653 mL	0.3264 mL	0.6528 mL	1.6320 mL
	40 mM	0.0490 mL	0.2448 mL	0.4896 mL	1.2240 mL
	50 mM	0.0392 mL	0.1958 mL	0.3917 mL	0.9792 mL
	60 mM	0.0326 mL	0.1632 mL	0.3264 mL	0.8160 mL
	80 mM	0.0245 mL	0.1224 mL	0.2448 mL	0.6120 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

N-Dodecyl-β-D-maltoside Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Dodecyl-β-D-maltoside69227-93-6Lauryl MaltosideDNA/RNA SynthesisDetergentSurfactantRCsRhodopseudomonas spheroides R-26ReactivationAluminaTitanium dioxideHematiteInhibitorinhibitorinhibit

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N-Dodecyl-β-D-maltoside (Synonyms: Lauryl Maltoside)

Customer Review

Other Forms of N-Dodecyl-β-D-maltoside:

N-Dodecyl-β-D-maltoside Related Antibodies

5 Publications Citing Use of MCE N-Dodecyl-β-D-maltoside

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All DNA/RNA Synthesis Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

N-Dodecyl-β-D-maltoside Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

N-Dodecyl-β-D-maltoside Related Classifications

Keywords:

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Customer Review

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SAFETY DATA SHEET (SDS)

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