NAD+ (GMP Like)  (Synonyms: β-DPN (GMP Like); β-NAD (GMP Like); β-Nicotinamide Adenine Dinucleotide (GMP Like))

NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

NAD+ (GMP Like) is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. NAD+ (GMP Like) is the oxidized form of NADH^[1]. NAD+ (GMP Like) is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (Nadide) ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oral NAD+ (GMP Like) supplementation has been used to combat simple fatigue as well as such mysterious and energy-sapping disorders as chronic fatigue syndrome and fibromyalgia^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

663.43

C₂₁H₂₇N₇O₁₄P₂

53-84-9

Powder

White to off-white

O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122(6): p. 253-70.  [Content Brief]

  [2]. Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem, 2006. 75: p. 69-92.  [Content Brief]

  [3]. Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103(20): p. 7607-12.  [Content Brief]