53-84-9
53-84-9
Chemical Structure
NAD+
Synonym(s): β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide
- CAS No.: 53-84-9
- Formula:C21H27N7O14P2
- Molecular Weight:663.43
IUPAC Name: 1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-3-carbamoylpyridin-1-ium
InChIKey: BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES: O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5
Biological Activity: NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NAD+ | 99.96% | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. | ||||||||||||||||||||
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NAD+ (GMP Like) | 99.79% | NAD+ (GMP Like) is NAD+ (HY-B0445) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. | ||||||||||||||||||||
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NAD+-d4 | 98.32% | NAD+-d4 is the deuterium-labeled NAD+ (HY-B0445). NAD+-d4 is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. | ||||||||||||||||||||
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NAD+-13C5 ammonium | 98.89% | NAD+-13C5 (ammonium) is the 13C labled NAD+ (HY-B0445), with an ammonium. | ||||||||||||||||||||
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NADP | 99.70% | NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes. | ||||||||||||||||||||
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3-Acetylpyridine adenine dinucleotide, 95% | 95.07% | 3-Acetylpyridine adenine dinucleotide, 95% (3-APAD, 95%)is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 95% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite. | ||||||||||||||||||||
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N6-(2-Aminoethyl)-NAD+ | N6-(2-Aminoethyl)-NAD+ (6-AE-NAD+) is an adenine-modified NAD analog with coenzyme activity and the property of targeting lactate dehydrogenase (LDH). N6-(2-Aminoethyl)-NAD+ undergoes transient affinity binding with LDH, thereby crosslinking the enzyme monolayer into an integrated electrode. N6-(2-Aminoethyl)-NAD+ is a component of the PQQ (HY-100196)-NAD+ binary interface, and supports the bioelectrocatalytic oxidation of lactate through PQQ-mediated immobilized NADH oxidation. | |||||||||||||||||||||
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Thionicotinamide adenine dinucleotide | 98.99% | Thionicotinamide adenine dinucleotide (Thio-NAD) is a thione-modified analog of the coenzyme nicotinamide adenine dinucleotide (NAD+). Thionicotinamide adenine dinucleotide can replace NAD+ in enzymatic reactions and shift the absorption peak to 405 nM, enabling sensitive, real-time kinetic detection of enzyme activity, which is particularly suitable for high-sensitivity diagnostic cyclic detection systems. | ||||||||||||||||||||
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Ara-F-NAD+ | Ara-F-NAD+ is an arabino analogue of NAD+. Ara-F-NAD+ is a potent, reversible and slow-binding CD38 NADase inhibitor. | |||||||||||||||||||||
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2'-Deoxy-NAD+ | 2'-Deoxy-NAD+ is a noncompetitive NAD+ inhibitor with a Ki of 32 μM. 2'-Deoxy-NAD+ can be utilized as a substrate to study the ADP-ribosyl transfer reaction. | |||||||||||||||||||||
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LCD36 | LCD36, a derivative of nicotinamide adenine dinucleotide (NAD), can be used for synthesis of PARP-1 tracers for positron emission tomography (PET) imaging of the enzyme activity of PARP-1. | |||||||||||||||||||||
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NAD sodium | 99.44% | NAD sodium is an orally effective cofactor and homeostatic regulator. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions that oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria, which indirectly generates ATP. NAD sodium can be used for the research of non-alcoholic fatty liver disease, obesity, and glucose intolerance. | ||||||||||||||||||||
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α-NAD | 98.00% | α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for reninase, functions as an analog of β-NAD, affects the kinetics of NAD-dependent enzymes, and also plays a critical role as a cofactor in mitochondrial redox reactions. | ||||||||||||||||||||
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NAD+ lithium | 99.49% | NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function. | ||||||||||||||||||||
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