1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Perindopril arginine

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection.

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Perindopril arginine

Perindopril arginine 화학구조

CAS No. : 612548-45-5

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5 g Ask For Quote & Lead Time

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제품 설명

Perindopril arginine is an angiotensin-converting enzyme inhibitor with hypotensive activity. Perindopril arginine is used to inhibit hypertension to lower blood pressure. Perindopril arginine, when used in combination with indapamide and amlodipine, can effectively lower blood pressure and provide better target organ protection[1].

Clinical Trial
분자량

542.67

화학식

C25H46N6O7

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(N)NCCC[C@H](N)C(O)=O.CCOC([C@H](CCC)N[C@@H](C)C(N1[C@]2([H])[C@](CCCC2)([H])C[C@H]1C(O)=O)=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

H2O : ≥ 100 mg/mL (184.27 mM)

DMSO : 6.48 mg/mL (11.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8427 mL 9.2137 mL 18.4274 mL
5 mM 0.3685 mL 1.8427 mL 3.6855 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.8427 mL 9.2137 mL 18.4274 mL 46.0685 mL
5 mM 0.3685 mL 1.8427 mL 3.6855 mL 9.2137 mL
10 mM 0.1843 mL 0.9214 mL 1.8427 mL 4.6069 mL
H2O 15 mM 0.1228 mL 0.6142 mL 1.2285 mL 3.0712 mL
20 mM 0.0921 mL 0.4607 mL 0.9214 mL 2.3034 mL
25 mM 0.0737 mL 0.3685 mL 0.7371 mL 1.8427 mL
30 mM 0.0614 mL 0.3071 mL 0.6142 mL 1.5356 mL
40 mM 0.0461 mL 0.2303 mL 0.4607 mL 1.1517 mL
50 mM 0.0369 mL 0.1843 mL 0.3685 mL 0.9214 mL
60 mM 0.0307 mL 0.1536 mL 0.3071 mL 0.7678 mL
80 mM 0.0230 mL 0.1152 mL 0.2303 mL 0.5759 mL
100 mM 0.0184 mL 0.0921 mL 0.1843 mL 0.4607 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Perindopril arginine
Cat. No.:
HY-169221
수량:
MCE Japan Authorized Agent: