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Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)  (Synonyms: PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed))

Cat. No.: HY-Y0850E Pureza: 96.30%
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Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients.

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Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) Estructura química

No. CAS : 9002-89-5

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Based on 3 publication(s) in Google Scholar

Other Forms of Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed):

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3 Publications Citing Use of MCE Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)

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Descripciòn

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients[1].

In Vitro

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) shows hemolysis index of 0.656% (sheep blood) and 0.028% (human blood)[6].
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) (5 g/25 cm3 deionised water) acts as a cell immobilization matrix for copper biosorption by yeast cells[7].
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) (1 mg/mL, 14 days) replaces serum albumin in leukemic cell (AML) cultures[8].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[8]

Cell Line: AML cells
Concentration: 1 mg/mL
Incubation Time: 14 days
Result: Supported growth of primary human AML samples cultured in the presence of cytokines and was almost equivalent to FBS-containing media.
In Vivo

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) (2000-5000 ppm, diet, daily, continuously for two generations) shows no adverse toxicological or reproductive effects in either parental animals (P0 and F1) or F1 and F2 offspring in Sprague–Dawley rats[2].
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (14C-labeled Polyvinyl alcohol, 3 mg/kg, daily) shows vaginal absorption in Fischer 344 rats[3].
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) shows an optimum viscosity range, with 12-15 cps of optimum viscosity in rabbits[4].
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) (Polyvinyl alcohol) (1 mL/day, s.c., 21 days prior to Gentamicin (HY-A0276A) induces an early sensitivity to gentamicin nephrotoxicity in rats[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

30000-70000 (Approximately)

Fòrmula

(C2H4O)n

No. CAS
Appearance

Solid

Color

White to off-white

SMILES

CCC(O)C.[n]

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Pureza y Documentación

Purity: 96.30%

Referencias
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)
Cat. No.:
HY-Y0850E
Cantidad:
MCE Japan Authorized Agent: