2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PTP1B-IN-13

PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.

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PTP1B-IN-13

PTP1B-IN-13 Estructura química

No. CAS : 650621-20-8

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5 mg En stock
10 mg En stock
50 mg   Obtener un presupuesto  
100 mg   Obtener un presupuesto  

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PTP1B-IN-13 Related Antibodies

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Descripciòn

PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.

Peso molecular

467.60

Fòrmula

C24H25N3O3S2
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC1=CC=CC=C1)NC(NC2=CC=C(S(=O)(NC3=CC=C(C)C(C)=C3)=O)C=C2)=S
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 166.67 mg/mL (356.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1386 mL 10.6929 mL 21.3858 mL
5 mM 0.4277 mL 2.1386 mL 4.2772 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1386 mL 10.6929 mL 21.3858 mL 53.4645 mL
5 mM 0.4277 mL 2.1386 mL 4.2772 mL 10.6929 mL
10 mM 0.2139 mL 1.0693 mL 2.1386 mL 5.3464 mL
15 mM 0.1426 mL 0.7129 mL 1.4257 mL 3.5643 mL
20 mM 0.1069 mL 0.5346 mL 1.0693 mL 2.6732 mL
25 mM 0.0855 mL 0.4277 mL 0.8554 mL 2.1386 mL
30 mM 0.0713 mL 0.3564 mL 0.7129 mL 1.7821 mL
40 mM 0.0535 mL 0.2673 mL 0.5346 mL 1.3366 mL
50 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0693 mL
60 mM 0.0356 mL 0.1782 mL 0.3564 mL 0.8911 mL
80 mM 0.0267 mL 0.1337 mL 0.2673 mL 0.6683 mL
100 mM 0.0214 mL 0.1069 mL 0.2139 mL 0.5346 mL
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PTP1B-IN-13 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PTP1B-IN-13650621-20-8PhosphataseInhibitorinhibitorinhibit

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Nombre del producto:
PTP1B-IN-13
Cat. No.:
HY-139640
Cantidad:
MCE Japan Authorized Agent:

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