21 Results for "

C18 fatty acid

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "C18 fatty acid" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-N0728
CAS No.: 463-40-1
Synonyms: ALA free base; C18:3 (9Z,12Z,15Z) free base; C18:3 n-3 free base
α-Linolenic acid (ALA (free base); C18:3 (9Z,12Z,15Z) (free base); C18:3 n-3 (free base)) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .
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12
12 Publications Verification
Cat. No.: HY-N0728A
CAS No.: 822-18-4
Synonyms: ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3
α-Linolenic acid sodium (ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3) is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .
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1 Cited Publications
Cat. No.: HY-N1446S2
CAS No.: 287100-82-7
Synonyms: 9-cis-Octadecenoic acid-13C18; 9Z-Octadecenoic acid-13C18
Oleic acid- 13C18 is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid . Oleic acid is a Na+/K+ ATPase activator .
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1 Cited Publications
Cat. No.: HY-B2219S2
CAS No.: 287100-83-8
Stearic acid- 13C18is the 13C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
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Cat. No.: HY-P4146
CAS No.: 2805997-46-8
Synonyms: BI 456906
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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Cat. No.: HY-N0728S3
CAS No.: 287111-28-8
α-Linolenic acid- 13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .
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Cat. No.: HY-160912
CAS No.: 1135000-36-0
Target:  

ELOVL

Research Areas:  

Metabolic Disease

ELOVL6-IN-5 is an orally active and selective elongase enzyme of long-chain fatty acid family 6 (ELOVL6) inhibitor with IC50 values of 85 nM and 38 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-5 shows >60-fold selectivity over other ELOVL family enzymes (ELOVL1, 2, 3, 5) and no effect on other lipid synthesis enzymes like ACC1, ACC2. ELOVL6-IN-5 reduces hepatic fatty acid composition ratio of C18 to C16 in diet-induced obesity (DIO) and KKAy mice. ELOVL6 inhibition by ELOVL6-IN-5 does not improve insulin resistance. ELOVL6-IN-5 can be used for the research of metabolic disease .
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Cat. No.: HY-113873
CAS No.: 105099-89-6
Research Areas:  

Metabolic Disease

10-Thiastearic acid inhibits desaturation of stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .
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Cat. No.: HY-P4146A
Synonyms: BI 456906 TFA
Target:  

GLP Receptor GCGR

Research Areas:  

Metabolic Disease

Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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Cat. No.: HY-164412
CAS No.: 85082-02-6
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Phosphatidylcholine (C18:2,C20:4) is a phosphatidylcholine species containing linoleic acid (C18:2) and arachidonic acid (C20:4) as fatty acid components, that can be isolated from egg yolk, red blood cell membranes of rat, rabbit, human, and dog. Phosphatidylcholine (C18:2,C20:4) can be used as a biomarker for the research of Alzheimer's disease .
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Cat. No.: HY-E70271
CAS No.: 27843-61-4
Synonyms: 6Z,9Z,12Z-Octadecatrienoyl-coenzyme A; γ-Linolenoylcoenzyme A; 6Z,9Z,12Z-Octadecatrienoyl-CoA
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

γ-Linolenoyl-CoA (C18:3(n6)-CoA) is a fatty acyl-CoA that can be used for lipidomics analysis of fatty acid-coenzyme A (FA-CoA) through LCMS/MS .
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Cat. No.: HY-W127393
CAS No.: 177158-21-3
Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.
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Cat. No.: HY-P4146B
Synonyms: BI 456906 sodium
Target:  

GLP Receptor GCGR

Research Areas:  

Metabolic Disease

Survodutide (BI 456906) sodium is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide sodium, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide sodium has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
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Cat. No.: HY-131701
CAS No.: 109785-20-8
Synonyms: C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine; Lyso-Lactosylceramide (synthetic)
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Lactosyl-C18-sphingosine (C18 Lactosyl(β) Ceramide; Lactosyl Sphingosine) is a bioactive sphingolipid that is a form of lactosylceramide but lacks the fatty acyl group. Lysolactosylceramide (1-50 μM) reduces the viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosyl-C18-sphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosyl-C18-sphingosine is a lysoganglioside GM3.
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Cat. No.: HY-W127487
CAS No.: 479050-96-9
Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.
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Cat. No.: HY-114773
CAS No.: 216596-71-3
Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.
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Cat. No.: HY-W332206
CAS No.: 125306-83-4
Target:  

Herbicide

Research Areas:  

Metabolic Disease

Cafenstrole acts as a herbicide. Cafenstrole is a potent inhibitor of microsomal elongase enzyme involved in the biosynthesis of fatty acids with alkyl chains longer han C18 .
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Cat. No.: HY-185225
CAS No.: 163069-97-4
Target:  

Drug Derivative

Research Areas:  

Others

cis-Vaccenic acid NHS ester is an N-hydroxysuccinimide (NHS)-activated ester derivative of cis-vaccenic acid (HY-113427A) (C18:1 n-7), which is commonly used as a fatty acid labeling reagent or covalent modification reagent .
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Cat. No.: HY-169872
CAS No.: 4552-19-6
17-Hydroxystearic acid isolable from Torulopsis magnoliae fermentation oil. 17-Hydroxystearic acid is a saturated C18 ω2-hydroxy fatty acid existing in D- and L-enantiomeric forms .
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Cat. No.: HY-21268S
Synonyms: Linolenic acid methyl ester-13C18
Methyl linolenate- 13C18 is the 13C labeled Methyl linolenate . Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids . The IC50 is 60 uM .
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