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Results for "

Culex pipiens

" in MedChemExpress (MCE) Product Catalog:

11

阻害剤およびアゴニスト

4

天然物

製品番号 製品名 Target 研究分野 構造式
  • HY-134891
    HMBPP lithium

    (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium

    		 Nuclear Factor of activated T Cells (NFAT) Infection Inflammation/Immunology
    HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .
    HMBPP lithium
  • HY-W099479
    Insect repellent M 3535

    Ethyl butylacetylaminopropionate; IR-3535

    		 Environmental Pollutants Apoptosis Reactive Oxygen Species (ROS) Parasite SOD Infection Inflammation/Immunology
    Insect repellent M 3535 (Ethyl butylacetylaminopropionate) is a broad-spectrum, mild insect repellent based on the structure of β-alanine. Insect repellent M 3535 exerts repellent effects by interfering with the olfaction of mosquitoes, but it poses risks of developmental and cardiac toxicity to aquatic organisms such as zebrafish embryos in aquatic environments, and can activate oxidative stress responses .
    Insect repellent M 3535
  • HY-W643128
    Carlina oxide

    		Cholinesterase (ChE) Infection
    Carlina oxide is an AChE inhibitor and antioxidant that kills Culex pipiens larvae (LC50=1.39 μg/mL). Carlina oxide is cytotoxic to vertebrate cells, human dermis, HCT116 and MDA-MB231 cell lines .
    Carlina oxide
  • HY-175607
    AChE/nAChR-IN-1

    		Cholinesterase (ChE) nAChR Infection Neurological Disease
    AChE/nAChR-IN-1 (Compound 1a) is dual-functional inhibitor of AChE and nAChR. AChE/nAChR-IN-1 has potent toxicity and larvicidal effectiveness against Culex pipiens larvae with a LC50 of 4 ng/mL. AChE/nAChR-IN-1 can be used as larvicides for mosquito-borne diseases research .
    AChE/nAChR-IN-1
  • HY-173073
    Insecticidal agent 20

    		Insecticide nAChR Infection
    Insecticidal agent 20 (Compound 17) is an insecticide that can bind to AChBP. Insecticidal agent 20 exhibits good insecticidal activity against the larvae (LC50: 1.57 ppm) and pupae (LC50: 4.17 ppm) of Culex pipiens .
    Insecticidal agent 20
  • HY-159148
    AChE-IN-70

    		Cholinesterase (ChE) Others
    AChE-IN-70 (compound 4) is a AChE inhibitor. AChE-IN-70 shows larvicidal activity against mosquito larvae (Culex pipiens L.). and can be used for study of mosquito control .
    AChE-IN-70
  • HY-173413
    Insecticidal agent 21

    		Insecticide Cholinesterase (ChE) nAChR Sodium Channel GABA Receptor Others
    Insecticidal agent 21 (Compound 6) is an insecticide that is effective against Culex pipiens larvae (LC50: 0.4 μg/mL). Insecticidal agent 21 achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors (nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR)). Insecticidal agent 21 has a strong insecticidal effect and can be used in the development of new insecticides to address the problem of mosquito resistance to traditional insecticides .
    Insecticidal agent 21
  • HY-N13754
    Leptostachyol acetate

    		Parasite Infection
    Leptostachyol acetate is a lignan compound that can be isolated from the roots of Phryma leptostachya var. asiatica. Leptostachyol acetate exhibits larvicidal activity against mosquito larvae, with LC50 values of 0.41, 2.1, and 2.3 ppm against third instar larvae of Culex pipiens pallens, Aedes aegypti, and Ocheratatos togoi, respectively. Leptostachyol acetate can be used for research on mosquito larval control .
    Leptostachyol acetate
  • HY-180778
    Insecticidal agent 28

    		Insecticide Cholinesterase (ChE) Infection
    Insecticidal agent 28 (Compound 10) is an insecticide targeting the Culex pipiens. Insecticidal agent 28 exhibits LC₅₀ values for killing larvae and adults of 40.15 ppm and 55.02 ppm respectively. Insecticidal agent 28 inhibits the acetylcholinesterase (AchE) of the Anopheles gambiae. Insecticidal agent 28 shows lower cytotoxicity .
    Insecticidal agent 28
  • HY-181706
    Insecticidal agent 29

    		Insecticide Infection
    Insecticidal agent 29 is a pyrethroid incorporating a pyridine heterocycle and insecticide. Insecticidal agent 29 exhibits insecticidal activity against Culex pipiens Pallens larvae, Aphis laburni Kaltenbach, and aphids. Insecticidal agent 29 shows inactivity against Tetranychus cinnabarinus Boisduval .
    Insecticidal agent 29
  • HY-N14120
    Opoponax oil

    Opopanax oil

    		 Insecticide Others
    Opoponax oil is an effective insecticide against mosquito larvae .
    Opoponax oil

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