Insect repellent M 3535
Based on 1 Customer Validation
Insect repellent M 3535 (Ethyl butylacetylaminopropionate) is a broad-spectrum, mild insect repellent based on the structure of β-alanine. Insect repellent M 3535 exerts repellent effects by interfering with the olfaction of mosquitoes, but it poses risks of developmental and cardiac toxicity to aquatic organisms such as zebrafish embryos in aquatic environments, and can activate oxidative stress responses.
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- Pureza : 99.70%
- No. CAS: 52304-36-6
- Fòrmula: C11H21NO3
- Peso molecular:215.29
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
In Vitro
The combination of Insect repellent M 3535 (10%; 30 min) and 1% supercritical cinnamon oil at a ratio of 1:1 exhibits aromatic repellent activity against Culex pipiens pallens[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wild-type zebrafish (Danio rerio) and transgenic lines Tg(myl7:GFP), Tg(myl7:GFP;gata1:Dsred)
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Dosage:10 mg/L, 20 mg/L, 30 mg/L
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Administration:aquatic immersion; daily solution renewal; 5.5 hpf to 72 hpf
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Result:Reduced body length, slowed yolk absorption, caused spinal curvature and pericardial edema, decreased heart rate, impaired cardiac looping and pumping function, dysregulated cardiac developmental genes (nkx2.5, myh6, tbx5a, vmhc, gata4, tbx2b).
Elevated ROS and MDA levels, lowered CAT and SOD activities, upregulated apoptosis‑related genes (bax/bcl2, p53, caspase9, caspase3), and triggered apoptosis.
Chemical Information
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No. CAS 52304-36-6
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Appearance Liquid (Density: 0.988±0.06 g/cm3)
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Peso molecular 215.29
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Fòrmula C11H21NO3
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Color Colorless to light yellow
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SMILES
CCCCN(CCC(=O)OCC)C(=O)C
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Synonyms
Ethyl butylacetylaminopropionate; IR-3535
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvente y solubilidad
In Vitro:
DMSO : ≥ 100 mg/mL (464.49 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6449 mL | 23.2245 mL | 46.4490 mL | 116.1224 mL |
| 5 mM | 0.9290 mL | 4.6449 mL | 9.2898 mL | 23.2245 mL | |
| 10 mM | 0.4645 mL | 2.3224 mL | 4.6449 mL | 11.6122 mL | |
| 15 mM | 0.3097 mL | 1.5483 mL | 3.0966 mL | 7.7415 mL | |
| 20 mM | 0.2322 mL | 1.1612 mL | 2.3224 mL | 5.8061 mL | |
| 25 mM | 0.1858 mL | 0.9290 mL | 1.8580 mL | 4.6449 mL | |
| 30 mM | 0.1548 mL | 0.7741 mL | 1.5483 mL | 3.8707 mL | |
| 40 mM | 0.1161 mL | 0.5806 mL | 1.1612 mL | 2.9031 mL | |
| 50 mM | 0.0929 mL | 0.4645 mL | 0.9290 mL | 2.3224 mL | |
| 60 mM | 0.0774 mL | 0.3871 mL | 0.7741 mL | 1.9354 mL | |
| 80 mM | 0.0581 mL | 0.2903 mL | 0.5806 mL | 1.4515 mL | |
| 100 mM | 0.0464 mL | 0.2322 mL | 0.4645 mL | 1.1612 mL |
Insect repellent M 3535 Related Classifications
HY-W099479 Related Classifications
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Keywords
- Insect repellent M 3535
- 52304-36-6
- Ethyl butylacetylaminopropionate
- IR-3535
- Insect repellent M3535
- Insect repellent M-3535
- IR3535
- IR 3535
- IR-3535
- Environmental Pollutants
- Apoptosis
- Parasite
- Reactive Oxygen Species (ROS)
- SOD
- oxidative stress
- superoxide dismutase
- Culex pipiens pallens
- Aedes togoi
- reactive oxygen species
- catalase
- zebrafish embryos
- fleas
- apoptosis
- Aedes albopictus
- Inhibitor
- inhibitor
- inhibit