Apiaceae

Edultin (Libanotine; Cnidimine) is an angular furanocoumarin. Edultin potently inhibits TPA (HY-18739)-induced early signals associated with tumor promotion (phospholipid metabolism). Edultin exerts mild inhibitory effects on some clinically isolated strains of Pseudomonas aeruginosa and Staphylococcus aureus. Edultin can be used in studies related to tumor promotion and bacterial infections.

6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC₅₀ of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC₅₀ of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM.

8-geranyloxy-5-methoxypsoralen is a BACE1 inhibitor with an IC₅₀ of 11.1 μM. 8-geranyloxy-5-methoxypsoralen potently inhibits BACE1 activity. 8-Geranyloxy-5-methoxypsoralen can be used for the research of Alzheimer's disease.

2-Carboxy-2-hydroxyethyl 12,16-heneicosadienoate (compound 2) is a fatty acid ester that can be found in the roots of Angelicae koreana Kitagawa (Bukkanghwal, BKH).

Saikosaponin bk1 is a NADPH-oxidase 5(NOX5) dehydrogenase domain binder and hepatoprotective agent. Saikosaponin bk1 forms stable interactions with the dehydrogenase domain of NOX5 from Cylindrospermum stagnale. Saikosaponin bk1 is applicable to research related to COVID-19 and alcoholic liver injury.

(Z)-6,7-Epoxyligustilide (Compound 8) is a Phthalide (HY-W015820) derivative found in the rhizomes of Ligusticum wallichii.

Penthoroside B is a natural phenolic compound.

Ligustilidiol is a natural product that can be found in Chuanxiong.

Penthoroside A is a phenylpropanoid derivative that can be isolated from the aerial parts of Oenanthe javanica.

1'-Hydroxyselinidin (3'-Angcloyl-cis-khcllactone) is a secondary metabolite.

Methoxylatifolone is a phenylpropanoid compound that can be isolated from the roots of Ferula communis.

Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes.

Ferolin is the agonist for farnesoid X receptor (FXR) with an EC₅₀ of 0.56 µM. Ferolin inhibits the expression of inflammatory genes (such as iNOS, IL-1β and TNFα) upon the FXR activation.

Celery Seed Extract is the extract of Celery Seed.

Spirohypertone B is a potent Tumor necrosis factor-α (TNF-α) inhibitor. Spirohypertone B protects L929 cells from death induced by co-incubation with TNF-α and Actinomycin D (HY-17559).

Falcarindiol 3-acetate (Compound 5) is a polyacetylenic secondary metabolite found in the underground parts of Pituranthus tortuosus, and is a derivative of the known antimicrobial compound Falcarindiol (HY-N0364).

Opoponax oil is an effective insecticide against mosquito larvae.