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Edultin (Libanotine; Cnidimine) is an angular furanocoumarin. Edultin potently inhibits TPA (HY-18739)-induced early signals associated with tumor promotion (phospholipid metabolism). Edultin exerts mild inhibitory effects on some clinically isolated strains of Pseudomonas aeruginosa and Staphylococcus aureus. Edultin can be used in studies related to tumor promotion and bacterial infections.

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Edultin

Edultin Chemical Structure

CAS No. : 15591-75-0

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Description

Edultin (Libanotine; Cnidimine) is an angular furanocoumarin. Edultin potently inhibits TPA (HY-18739)-induced early signals associated with tumor promotion (phospholipid metabolism). Edultin exerts mild inhibitory effects on some clinically isolated strains of Pseudomonas aeruginosa and Staphylococcus aureus. Edultin can be used in studies related to tumor promotion and bacterial infections[1][2].

In Vitro

Edultin (50 μg/mL) inhibits TPA-stimulated 32Pi incorporation into phospholipids of HeLa cells by 97.3%[1].
Edultin (8-128 mg/L) exhibits slight antibacterial activity at 128 mg/L, inhibiting 4 of 8 Pseudomonas aeruginosa clinical isolates and 1 of 16 Staphylococcus aureus clinical isolates, with no activity observed at concentrations of 8, 25, or 32 mg/l[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

386.40

Formula

C21H22O7

CAS No.
SMILES

C/C=C(C)\C(O[C@@H]1C2=C(O[C@@H]1C(C)(C)OC(C)=O)C=CC(C=C3)=C2OC3=O)=O

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Edultin
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HY-N19810
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