6-Isopentenyloxyisobergapten
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC50 of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC50 of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM.
For research use only. We do not sell to patients.
- CAS No.: 24099-29-4
- Formula: C17H16O5
- Molecular Weight:300.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6-Isopentenyloxyisobergapten (compound 4) (10-1000 μM; 7 days) shows stronger phytotoxic inhibitory activity against Agrostis stolonifera seeds than Lactuca sativa seeds[1].
6-Isopentenyloxyisobergapten (10-1000 μM; 4 days) exhibits concentration-dependent growth inhibitory activity in Lemna paucicostata plants, with an IC50 of 29 μM for the growth inhibition of Lemna paucicostata[1].
6-Isopentenyloxyisobergapten (compound 8) exhibits significant antimycobacterial activity against Mycobacterium tuberculosis H37Ra, with a minimum inhibitory concentration (MIC) of 166.5 μM and an IC50 of 27.4 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 24099-29-4
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Molecular Weight 300.31
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Formula C17H16O5
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SMILES
C/C(C)=C\COC1=C(C(C=C2)=C(C3=C1C=CO3)OC2=O)OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sondhia S, et al. Phytotoxic furanocoumarins from the shoots of Semenovia transiliensis. Nat Prod Commun. 2012;7(10):1327-1330. [Content Brief]
[2]. O'Neill T,et al. The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarins. J Ethnopharmacol. 2013 May 2;147(1):232-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-Isopentenyloxyisobergapten Related Classifications
HY-W748468 Related Classifications
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