33 Results for "

DSG-PEG2000

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "DSG-PEG2000" in MCE Product Catalog:

Cat. No.: HY-W591381
CAS No.: 308805-39-2
Target:  

Liposome

Research Areas:  

Others

DSG-PEG2000 is a type of polyethylene glycol grease. DSG-PEG2000 can be used to prepare liposomes [2].
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Cat. No.: HY-P10392AF
Target:  

Wnt β-catenin

Research Areas:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
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Cat. No.: HY-P10896
CAS No.: 1446005-10-2
Target:  

Bombesin Receptor

Research Areas:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
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Cat. No.: HY-169232
Target:  

PROTACs PD-1/PD-L1

Research Areas:  

Cancer

PCC16 chloride is a dual PROTAC degrader targeting DHHC3 and PD-L1, with a DC50 of 0.103 μM for PD-L1 degradation. PCC16 chloride induces DHHC3 degradation via the ubiquitin-proteasome pathway by recruiting the CRBN E3 ubiquitin ligase (E3 ubiquitin ligase). By targeting DHHC3-which is essential for PD-L1 palmitoylation and membrane stability-PCC16 chloride reduces PD-L1 levels, decreases PD-L1 membrane retention time, and impairs its immunosuppressive function. PCC16 chloride enhances anti-tumor immunity by disrupting PD-L1-mediated immunosuppression. PCC16 chloride can be used in the research of immune checkpoint blockade-resistant cancers .
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Cat. No.: HY-187245A
Synonyms: DSG-PEG2000-CSRNLIDC
DSG-PEG2000-pPB (DSG-PEG2000-CSRNLIDC) is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and platelet-derived growth factor receptor β-binding peptide (pPB peptide (HY-P11549)) as the terminal targeting/functional ligand. DSG-PEG2000-pPB enables targeted delivery to fibrotic tissues and tumor stroma.
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Cat. No.: HY-182947A
DSG-PEG2000-Mannose is a conjugate composed of DSG, a PEG chain, and terminal mannose. DSG-PEG2000-Mannose combines the membrane compatibility of phospholipids with the targeted recognition capabilities of mannose, making it suitable for research in biomaterial construction and drug delivery.
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Cat. No.: HY-183170A
DSG-PEG2000-Biotin is a conjugate composed of DSG, PEG chains, and biotin. DSG-PEG2000-Biotin combines the membrane compatibility of phospholipids with the high affinity of biotin for avidin/streptavidin, enabling applications such as targeted drug delivery systems and nanoparticle modification.
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Cat. No.: HY-183171A
DSG-PEG2000-CHO is a conjugate composed of DSG, a PEG chain, and a terminal aldehyde group (-CHO). DSG-PEG2000-CHO combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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Cat. No.: HY-183132A
DSG-PEG2000-OH is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and terminal hydroxyl groups (-OH). DSG-PEG2000-OH combines the membrane compatibility of phospholipids with the flexibility of hydroxyl modification, making it suitable for research in biomaterial construction and drug delivery.
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Cat. No.: HY-183172A
DSG-PEG2000-Alkyne is a conjugate composed of DSG, a PEG chain, and a terminal alkyne group. DSG-PEG2000-Alkyne combines the membrane compatibility of phospholipids with the high reactivity of the alkyne group in click chemistry, making it suitable for research in biomaterial construction and drug delivery.
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Cat. No.: HY-183175A
CAS No.: 3101670-37-2
DSG-PEG2000-N3 is a conjugate composed of DSG, PEG chains, and terminal azido groups (-N3). DSG-PEG2000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-187315A
Synonyms: DSG-PEG2000-APWHLSSQYSR
DSG-PEG2000-CTP is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and CTP (cardiotropic targeting peptide) (HY-P4094) as the terminal targeting/functional ligand. DSG-PEG2000-CTP can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers, conferring cardiac targeting capability.
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Cat. No.: HY-183159A
DSG-PEG2000-Glucose is a conjugate composed of DSG, a PEG chain, and terminal glucose. DSG-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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Cat. No.: HY-183173A
DSG-PEG2000-COOH is a conjugate composed of DSG, a PEG chain, and a terminal carboxyl group (-COOH). The carboxyl group in DSG-PEG2000-COOH can form an amide bond with a primary amine via EDC/NHS activation, enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126A
DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183104A
DSG-PEG2000-NHS is a conjugate composed of DSG, PEG chains, and terminal active esters (NHS). The NHS ester in DSG-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptides, and small molecules modified with amino groups) to form stable amide bonds, enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-187239A
DSG-PEG2000-TAT is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, PEG, and TAT peptide (YGRKKRRQRRR) (HY-P0281) as the terminal targeting/functional ligand. DSG-PEG2000-TAT can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against non-specific cell membrane penetration (heparan sulfate proteoglycans).
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Cat. No.: HY-187188A
DSG-PEG2000-WYRGRL is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and WYRGRL peptide (HY-P10739)as the terminal targeting/functional ligand. DSG-PEG2000-WYRGRL can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against specific cell surface receptors in tumor and inflammatory microenvironments.
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Cat. No.: HY-184567A
DSG-PEG2000-iRGD is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and iRGD peptide (HY-P0122) as the terminal targeting/functional ligand. DSG-PEG2000-iRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against sequential binding to αv integrins on tumor vasculature → neuropilin-1 (NRP1) in tumor tissue.
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Cat. No.: HY-187244A
DSG-PEG2000-cRGD is a functionalized PEGylated lipid conjugate composed of three modular components: distearoylglycerol (DSG) as the lipid anchoring group, a polyethylene glycol (PEG) spacer arm with a molecular weight of 2000 Da, and cyclic RGD peptide (cyclo(Arg-Gly-Asp)) as the terminal targeting/functional ligand. DSG-PEG2000-cRGD can be incorporated into liposomes, lipid nanoparticles (LNPs), or other nanocarriers to confer ligand-directed targeting capability against αvβ3/αvβ5 integrins on tumor vasculature and cancer cell surfaces.
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