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Cat. No.: HY-P3252AS

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Pegcetacoplan-¹³C₃,₁₅N TFA

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Based on 1 publication(s) in Google Scholar

Pegcetacoplan-¹³C₃,¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Pegcetacoplan TFA. Pegcetacoplan is a pegylated complement C3/C3b inhibitor. Pegcetacoplan acts by specifically binding to and inhibiting C3 and C3b, thereby suppressing the complement cascade at its proximal stage. Pegcetacoplan is not a known inhibitor or inducer of CYP450 isoenzymes. Pegcetacoplan can be used for the research of complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).

For research use only. We do not sell to patients.

Formula: (C₂H₄O)_nC₁₇₀H₂₄₈N₅₀O₄₇S₄·xC₂HF₃O₂

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

Pegcetacoplan-¹³C₃,₁₅N TFA Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Publications (1)
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Formula (C₂H₄O)_nC₁₇₀H₂₄₈N₅₀O₄₇S₄·xC₂HF₃O₂
Sequence

Ac-Ile-Cys-Val-Trp(Me)-Gln-Asp-Trp-Gly-Ala(13C3,15N)-His-Arg-Cys-Thr-PEG2-Lys-NH2(Cys and Cys bridge，Dimer with PEG40000)
Sequence Shortening

Ac-ICV-{Trp(Me)}-QDWG-{Ala(13C3,15N)}-HRCY-PEG2-K-NH2(Cys and Cys bridge，Dimer with PEG40000)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.