Search Result

Results for "

GDF-8

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (3) TGF-beta/Smad (4)
By Research Areas:	Cancer (1) Inflammation/Immunology (3) Metabolic Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99388

Trevogrumab 1 Publications Verification REGN-1033; SAR391786	TGF-beta/Smad	Metabolic Disease
Trevogrumab (REGN-1033) is a monoclonal antibody targeting *GDF8* (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .

HY-P99370

Landogrozumab 1 Publications Verification LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)	TGF-beta/Smad	Inflammation/Immunology Cancer
Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .

HY-P990993

Emugrobart GYM-329, RG6237, RG-70240	TGF-beta/Smad	Inflammation/Immunology
Emugrobart (GYM-329, RG6237, RG-70240) is a humanized IgG1κ antibody targeting myostatin (Myostatin; GDF8). Emugrobart binds to pro-myostatin and latent myostatin, blocking their cleavage into mature myostatin; it also has a clearance function, which transports bound myostatin for degradation and allows for cyclic reuse. Emugrobart enhances muscle strength in mouse models of muscle atrophy and increases muscle mass in cynomolgus monkeys. Emugrobart can be used in research on spinal muscular atrophy and facioscapulohumeral muscular dystrophy .

HY-P990733

Cibotercept KER-012	TGF-beta/Smad	Inflammation/Immunology
Cibotercept (KER-012) is a novel, modified, investigational activin receptor type IIB (ActRIIB) ligand trap designed to target select TGF-β ligands, including activins A and B, GDFs 8 and 11, to rebalance the defective activin receptor type II signaling observed in PAH .

HY-RS08731

MSTN Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MSTN Human Pre-designed siRNA Set A contains three designed siRNAs for MSTN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MSTN Human Pre-designed siRNA Set A MSTN Human Pre-designed siRNA Set A

HY-RS24617

Mstn Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mstn Rat Pre-designed siRNA Set A contains three designed siRNAs for Mstn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mstn Rat Pre-designed siRNA Set A Mstn Rat Pre-designed siRNA Set A

HY-RS18142

Mstn Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mstn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mstn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mstn Mouse Pre-designed siRNA Set A Mstn Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area	Image

HY-P99388

Trevogrumab 1 Publications Verification REGN-1033; SAR391786	TGF-beta/Smad	Metabolic Disease
Trevogrumab (REGN-1033) is a monoclonal antibody targeting *GDF8* (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .

HY-P99370

Landogrozumab 1 Publications Verification LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)	TGF-beta/Smad	Inflammation/Immunology Cancer
Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .

HY-P990993

Emugrobart GYM-329, RG6237, RG-70240	TGF-beta/Smad	Inflammation/Immunology
Emugrobart (GYM-329, RG6237, RG-70240) is a humanized IgG1κ antibody targeting myostatin (Myostatin; GDF8). Emugrobart binds to pro-myostatin and latent myostatin, blocking their cleavage into mature myostatin; it also has a clearance function, which transports bound myostatin for degradation and allows for cyclic reuse. Emugrobart enhances muscle strength in mouse models of muscle atrophy and increases muscle mass in cynomolgus monkeys. Emugrobart can be used in research on spinal muscular atrophy and facioscapulohumeral muscular dystrophy .

HY-P990733

Cibotercept KER-012	TGF-beta/Smad	Inflammation/Immunology
Cibotercept (KER-012) is a novel, modified, investigational activin receptor type IIB (ActRIIB) ligand trap designed to target select TGF-β ligands, including activins A and B, GDFs 8 and 11, to rebalance the defective activin receptor type II signaling observed in PAH .

Recombinant Proteins Recommended:

Growth Differentiation Factor-8 (GDF-8)

Species:	Human (8) Rat (5) Mouse (7) Cat (1)
Tag:	His (7) Tag Free (3) Avi (3)
Source:	HEK293 (9) CHO (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704631

	GDF-8 Protein, Human (CHO) Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Human	CHO
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human (CHO) is the recombinant human-derived GDF-8 protein, expressed by CHO, with tag free.

HY-P72632

	GDF-8 Protein, Human/Mouse/Rat (HEK293) 1 Publications Verification Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Mouse;Rat;Human	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (HEK293) is the recombinant rat-derived GDF-8 protein, expressed by HEK293 , with tag free.

HY-P704630

	GDF-8 Protein, Human (CHO, His) Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Rat;Mouse;Human	CHO
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human (CHO, His) is the recombinant rat/mouse/human-derived GDF-8 protein, expressed by CHO, with N-His labeled tag.

HY-P702874

	GDF-8 Protein, Human/Mouse/Rat (109a.a, HEK293) Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Mouse;Human;Rat	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (109a.a, HEK293) is the recombinant rat-derived GDF-8 protein, expressed by HEK293 , with tag free.

HY-P704236

	*Latent GDF-8* Protein, Mouse (HEK293, His)** Growth/differentiation factor 8; Latent GDF-8; LGDF-8; LMyostatin; LGDF8; LMstn	Mouse	HEK293

HY-P704015

	*Latent GDF-8* Protein, Human (HEK293, His)** Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Human	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. Latent GDF-8 Protein, Human (HEK293, His) is the recombinant human-derived Latent GDF-8 protein, expressed by HEK293, with N-His labeled tag.

HY-P705231

	GDF-8 Protein, Human/Mouse/Rat (Biotinylated, HEK293, His) Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Rat;Mouse;Human	HEK293

HY-P705393

	*Latent GDF-8* Protein, Human (Biotinylated, HEK293, His-Avi)** Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Human	HEK293

HY-P705261

	*Latent GDF-8* Protein, Mouse (Biotinylated, HEK293, His-Avi)** Growth/differentiation factor 8; Latent GDF-8; LGDF-8; LMyostatin; LGDF8; LMstn	Mouse	HEK293

HY-P700498

	MSTN Protein, Cat (HEK293, His) myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8	Cat	HEK293
	MSTN (Myostatin) serves as a dedicated negative regulator of skeletal muscle growth, forming homodimers through disulfide linkages. It inhibits WFIKKN2 activity through interaction and further contributes to its role in negatively modulating skeletal muscle growth by engaging with FSTL3. MSTN Protein, Cat (HEK293, His) is the recombinant cat-derived MSTN protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P702874Y

	GDF-8 Protein, Human/Mouse/Rat (Biotinylated, 109a.a, HEK293, Avi, Solution) Growth/differentiation factor 8; GDF-8; Myostatin; MSTN	Rat;Human;Mouse	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (Biotinylated, 109a.a, HEK293, Avi, Solution) is the recombinant rat/mouse/human-derived GDF-8 protein, expressed by HEK293, with C-Avi labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (3)
Reactivity:	Human (3)
Application:	IHC-P (2) WB (2) FC (2) ELISA (3)
Isotype:	IgG2b (2)
Conjugation:	Non-conjugated (3) Biotin (4)
Clonality:	Monoclonal (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85185

	GDF-8 Antibody (YA4877) MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin	WB, ELISA	Human
	GDF-8 Antibody (YA4877) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GDF-8.

HY-P83813

	MSTN Antibody (YA3510) GDF8; MSLHP	WB, IHC-P, FC, ELISA	Human
	MSTN Antibody (YA3510) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MSTN.

HY-P83813A

	MSTN Antibody (YA3510)(PBS only) GDF8; MSLHP	IHC-P, FC, ELISA	Human
	MSTN Antibody (YA3510) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MSTN.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS08731

MSTN Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
MSTN Human Pre-designed siRNA Set A contains three designed siRNAs for MSTN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24617

Mstn Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Mstn Rat Pre-designed siRNA Set A contains three designed siRNAs for Mstn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS18142

Mstn Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Mstn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mstn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: