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Cibotercept

(Synonyms: KER-012)
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Based on 1 Customer Validation

Cibotercept (KER-012) is a novel, modified, investigational activin receptor type IIB (ActRIIB) ligand trap designed to target select TGF-β ligands, including activins A and B, GDFs 8 and 11, to rebalance the defective activin receptor type II signaling observed in PAH.

For research use only. We do not sell to patients.

  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cibotercept
  • Experimental Validation Results for Cibotercept
  • Experimental Validation Results for Cibotercept
  • Cibotercept Chemical Structure
    Cibotercept Chemical Structure
CAS No.: 2769700-97-0
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Cibotercept Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All TGF-beta/Smad Isoforms

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100 mg

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Assay Types
  • 1/16

    FPIA_[PROTEIN]2-FC

  • 1/16

    Immobilized Activin A Protein, Human/Mouse/Rat (HEK293, HY-P70311) can bind Cibotercept. The EC50 for this effect is 32.97 ng/mL.

  • 1/16

    Immobilized GDF-11/BMP-11 Protein, Human (HEK293, solution, HY-P70222Y) can bind Cibotercept. The EC50 for this effect is 66.34 ng/mL.

  • Cibotercept Chemical Structure
    1/16
  • Cibotercept
  • Immobilized Activin A Protein, Human/Mouse/Rat (HEK293, HY-P70311) can bind Cibotercept. The EC50 for this effect is 32.97 ng/mL.
  • Immobilized GDF-11/BMP-11 Protein, Human (HEK293, solution, HY-P70222Y) can bind Cibotercept. The EC50 for this effect is 66.34 ng/mL.
  • FPIA_[PROTEIN]2-FC