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MSTN Antibody (YA3510)

(Synonyms: GDF8; MSLHP)
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Based on 1 Customer Validation

MSTN Antibody (YA3510) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MSTN.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    WB, IHC-P, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for MSTN Antibody (YA3510)
  • MSTN Antibody (YA3510) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:1000 1:200-1:400 1:10000

Product Details

Description

MSTN Antibody (YA3510) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to MSTN.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 40 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 43 kDa
Immunogen

Purified recombinant fragment of human MSTN (AA:24-266) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2b

RRID

AB_3718772

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for MSTN Antibody (YA3510)
    Flow cytometric analysis of 1X10^6 Hela cells labeling MSTN Antibody(HY-P83813

Background

  • Function

    MSTN acts specifically as a negative regulator of skeletal muscle growth

  • Subcellular Localization

    Secreted

  • Subunit

    Homodimer; disulfide-linked (PubMed:27625211). Interacts with WFIKKN2, leading to inhibit its activity (PubMed:12595574). Interacts with FST3 (PubMed:17878677)

  • SwissProt ID

    O14793

  • Gene ID
    2660 [NCBI]
  • Synonyms

    GDF8; MSLHP

MSTN Antibody (YA3510) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Flow cytometric analysis of 1X10^6 Hela cells labeling MSTN Antibody(HY-P83813

  • MSTN Antibody (YA3510) Product Image
    1/16
  • Experimental Validation Results for MSTN Antibody (YA3510)
  • MSTN Antibody (YA3510) Product Image
  • Experimental Validation Results for MSTN Antibody (YA3510)
    1/1
    MedChemExpress Validation
     Flow cytometric analysis of 1X10^6 Hela cells labeling MSTN Antibody(HY-P83813
  • Experimental Validation Results for MSTN Antibody (YA3510)
  • MSTN Antibody (YA3510) Product Image
    MedChemExpress Validation

    Flow cytometric analysis of 1X10^6 Hela cells labeling MSTN Antibody(HY-P83813

  • MSTN Antibody (YA3510) Product Image FC