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GPDH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (1) Endogenous Metabolite (8) HIF/HIF Prolyl-Hydroxylase (1) Insecticide (1) Phosphoglycerate Dehydrogenase (PHGDH) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (2) Infection (2) Metabolic Disease (7)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) siRNAs (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113128A

sn-Glycerol 3-phosphate lithium	Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

HY-113128

sn-Glycerol 3-phosphate	Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

HY-121970

iGP-1	Phosphoglycerate Dehydrogenase (PHGDH) Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase	Metabolic Disease
iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC₅₀s of 6.3 μM and 13.6 μM for rat mGPDH activity and H₂O₂ production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways .

HY-116934

5-Pentadecylresorcinol 1 Publications Verification Adipostatin A	Insecticide	Infection Cancer
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC₅₀ of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-P2765

Glycerol-3-phosphate dehydrogenase, rabbit muscle GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate dehydrogenase, rabbit muscle (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate. Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD ⁺ and energy supply .

HY-P2765A

Glycerol-3-phosphate dehydrogenase, microorganism GPDH, microorganism; α-Glycerophosphate dehydrogenase, microorganism; Glycerol phosphate dehydrogenase, microorganism	Endogenous Metabolite	Metabolic Disease
Glycerol-3-phosphate dehydrogenase, microorganism (GPDH, microorganism) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate to sn-glycerol 3-phosphate.Glycerol-3-phosphate dehydrogenase is a glycolytic enzyme and is responsible for the re-oxidation of NADH to NAD ⁺ and energy supply .

HY-127127

Deamino-NAD	Endogenous Metabolite	Others
Deamino-NAD is a structural analog of NAD+ (HY-B0445). Deamino-NAD is involved in glycolysis as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH), with a K_m of 2300 pm, and a K_d of 112 pm .

HY-113128B

sn-Glycerol 3-phosphate biscyclohexylammonium salt	Endogenous Metabolite	Metabolic Disease
sn-Glycerol 3-phosphate biscyclohexylammonium salt is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate biscyclohexylammonium salt from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate biscyclohexylammonium salt for lipid metabolism .

HY-RS17954

Gpd2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gpd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gpd2 Mouse Pre-designed siRNA Set A Gpd2 Mouse Pre-designed siRNA Set A

HY-127127A

Deamino-NAD sodium	Aldehyde Dehydrogenase (ALDH) Endogenous Metabolite	Metabolic Disease
Deamino-NAD sodium is a structural analog of NAD+ (HY-B0445). Deamino-NAD sodium is involved in glycolysis as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH), with a K_m of 2300 pm, and a K_d of 112 pm .

HY-116934R

5-Pentadecylresorcinol (Standard) Adipostatin A (Standard)	Reference Standards Others	Infection Cancer
5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

HY-RS25101

Gpd1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gpd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gpd1 Rat Pre-designed siRNA Set A Gpd1 Rat Pre-designed siRNA Set A

HY-E70417

Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae GPDH, Saccharomyces cerevisiae	Endogenous Metabolite	Others
Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is an enzyme involved in glycerol metabolism and energy production, responsible for catalyzing the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP). Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, is the rate-limiting enzyme in glycerol production in Saccharomyces cerevisiae, and helps Saccharomyces cerevisiae adapt to high osmotic environments by regulating glycerol production and accumulation. Glycerol-3-phosphate dehydrogenase, Saccharomyces cerevisiae, can be used in research within the field of metabolic engineering .

sn-Glycerol 3-phosphate lithium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

sn-Glycerol 3-phosphate	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

5-Pentadecylresorcinol 1 Publications Verification Adipostatin A	Infection Structural Classification Ardisia brevicaulis Diels Classification of Application Fields Phenols Polyphenols Plants Myrsinaceae Disease Research Fields Source Classification	Insecticide
5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC₅₀ of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

Deamino-NAD	Microorganisms Source Classification	Endogenous Metabolite
Deamino-NAD is a structural analog of NAD+ (HY-B0445). Deamino-NAD is involved in glycolysis as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH), with a K_m of 2300 pm, and a K_d of 112 pm .

sn-Glycerol 3-phosphate biscyclohexylammonium salt	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate biscyclohexylammonium salt is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate biscyclohexylammonium salt from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate biscyclohexylammonium salt for lipid metabolism .

5-Pentadecylresorcinol (Standard) Adipostatin A (Standard)	Structural Classification Ardisia brevicaulis Diels Phenols Polyphenols Plants Myrsinaceae Source Classification	Reference Standards Others
5-Pentadecylresorcinol (Standard) is the analytical standard of 5-Pentadecylresorcinol. This product is intended for research and analytical applications. 5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70320

	GPD1 Protein, Human (HEK293, His) rHuGlycerol-3-phosphate dehydrogenase [NAD(+)] cytoplasmic/GPD1, His; Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic; GPD-C; GPDH-C; GPD1	Human	HEK293
	GPD1 protein, a glycerol-3-phosphate dehydrogenase, crucially converts glycerol-3-phosphate to dihydroxyacetone phosphate, a key step in glycolysis and gluconeogenesis. Its enzymatic activity regulates cellular energy metabolism and glycerolipid biosynthesis, essential for maintaining cellular homeostasis and energy production. GPD1's role makes it a key player in metabolic processes with implications for various physiological functions. GPD1 Protein, Human (HEK293, His) is the recombinant human-derived GPD1 protein, expressed by HEK293 , with C-6*His labeled tag.

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Gpd2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Gpd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gpd1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Gpd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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