sn-Glycerol 3-phosphate lithium
Based on 1 Customer Validation
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism.
For research use only. We do not sell to patients.
- Purity: 99.98%
- Formula: C3H7Li2O6P
- Molecular Weight:183.94
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
The cytosolic GPDH consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP), and the resulting sn-Glycerol 3-phosphate lithium passes through the permeable mitochondrial outer membrane. sn-Glycerol 3-phosphate lithium is reoxidized to DHAP at the outer surface of the inner mitochondrial membrane by the mitochondrial FAD-GPDH, which donates the electrons to the mitochondrial ubiquinone pool. The DHAP is subsequently channeled back to the cytosolic compartment[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 183.94
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Formula C3H7Li2O6P
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Color White to off-white
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SMILES
O[C@H](CO)COP(O[Li])(O[Li])=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 50 mg/mL (271.83 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (271.83 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Frasson D, et al. The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats. Metabolism. 2012 Oct;61(10):1473-85. [Content Brief]
[2]. Shen W, et al. Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell. 2006 Feb;18(2):422-41. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.4366 mL | 27.1828 mL | 54.3656 mL | 135.9139 mL |
| 5 mM | 1.0873 mL | 5.4366 mL | 10.8731 mL | 27.1828 mL | |
| 10 mM | 0.5437 mL | 2.7183 mL | 5.4366 mL | 13.5914 mL | |
| 15 mM | 0.3624 mL | 1.8122 mL | 3.6244 mL | 9.0609 mL | |
| 20 mM | 0.2718 mL | 1.3591 mL | 2.7183 mL | 6.7957 mL | |
| 25 mM | 0.2175 mL | 1.0873 mL | 2.1746 mL | 5.4366 mL | |
| 30 mM | 0.1812 mL | 0.9061 mL | 1.8122 mL | 4.5305 mL | |
| 40 mM | 0.1359 mL | 0.6796 mL | 1.3591 mL | 3.3978 mL | |
| 50 mM | 0.1087 mL | 0.5437 mL | 1.0873 mL | 2.7183 mL | |
| 60 mM | 0.0906 mL | 0.4530 mL | 0.9061 mL | 2.2652 mL | |
| 80 mM | 0.0680 mL | 0.3398 mL | 0.6796 mL | 1.6989 mL | |
| 100 mM | 0.0544 mL | 0.2718 mL | 0.5437 mL | 1.3591 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
sn-Glycerol 3-phosphate lithium Related Classifications
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